Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 1621-1640 of 3,347 trials

Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion

NCT01997190

This is a phase I study of intrapleural AdV-tk therapy in patients with malignant pleural effusion (MPE). The primary objective is to test the safety of intrapleural AdV-tk therapy. Secondary objectives are to evaluate clinical efficacy and biologic activity

Malignant Pleural EffusionLung CancerMesothelioma+2 more

Candel Therapeutics, Inc.19 participantsStarted Oct 2013

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

Maximizing Outcomes in Treating Acute Migraine

NCT03896009

AXS-07 is an oral, investigational medicine consisting of MoSEIC meloxicam and rizatriptan, which is being developed for the acute treatment of migraine with or without aura in adults. AXS-07 tablets are formulated to provide an enhanced rate of absorption of meloxicam. This study is designed to evaluate the efficacy and safety of AXS-07 compared to meloxicam, rizatriptan, and placebo for the treatment of a migraine attack. This is a randomized, double-blind, 4-arm, parallel group, single-dose, placebo-controlled trial. Subjects who successfully complete screening and continue to meet all entry criteria will be randomly assigned to take one dose of either AXS-07, meloxicam, rizatriptan, or placebo upon the occurrence of a qualifying migraine.

Migraine

Axsome Therapeutics, Inc.1,594 participantsStarted Mar 2019

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Mobile, Alabama, United States +82 more locations

Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion

Maximizing Outcomes in Treating Acute Migraine

Rheumatoid Arthritis Trials in Other Cities

Arimoclomol in Amyotropic Lateral Sclerosis

A Study of CART-PSMA-TGFβRDN in Patients With Metastatic Castration Resistant Prostate Cancer

KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion

ADVM-022 Intravitreal Gene Therapy for Wet AMD

Does Early Elbow Motion Improve Patient Outcomes After Surgically Treated Elbow Fractures?

Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)

Safety, Tolerability, and Efficacy of Aflibercept in Patients With Neovascular Age-Related Macular Degeneration

A Phase 2 Study of Sitravatinib in Combination With PD-(L)1 Checkpoint Inhibitor Regimens in Patients With Advanced or Metastatic Urothelial Carcinoma

CC486-CHOP in Patients With Previously Untreated Peripheral T-cell Lymphoma

A Study of FT-7051 in Men With MCRPC

Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects

Zevalin® Followed by Rituxan® Maintenance in Previously Treated Low Grade Non-Hodgkin's Lymphoma

A Study to Evaluate Safety and Immunogenicity of One or Two Booster Vaccinations With H5N6 Influenza Vaccine in Adults Primed With H5N1 Influenza Vaccine or Unprimed

Nano-Pulse Stimulation (NPS) in Seborrheic Keratosis Study

A Study Evaluating Venetoclax (ABT-199) in Multiple Myeloma Subjects Who Are Receiving Bortezomib and Dexamethasone as Standard Therapy

Other Conditions in Philadelphia