Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 1201-1220 of 3,347 trials

ASSIST: Treatment for Childhood Apraxia of Speech

NCT03903120

Childhood apraxia of speech (CAS) is a pediatric motor speech disorder that impairs the planning of movements needed for intelligible speech. Children with CAS often show little or slow progress in standard speech therapy. This research is a Phase 1 study that tests initial efficacy and optimal parameters of a theoretically based integral stimulation treatment called ASSIST (Apraxia of Speech Systematic Integral Stimulation Treatment). In three small randomized group design studies, children (N=20 per study) receive 16 hours of individual ASSIST. The three studies systematically investigate treatment intensity (2 vs. 4 weeks) and two critical aspects of target selection: complexity (simple vs. complex target) and lexicality (words vs. nonwords). Each study also systematically examines the effect of treatment on functional outcome measures, including parent ratings of intelligibility and communicative participation, and objective intelligibility measures obtained from unfamiliar listeners.

Childhood Apraxia of Speech

Temple University420 participantsStarted Apr 2019

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

NCT03452111

The long term objective is to develop a gel to be used as a male contraceptive.

HealthyMenMale Contraception

Premier Research420 participantsStarted Oct 2018

Sacramento, California, United States • Torrance, California, United States • Denver, Colorado, United States +14 more locations

ASSIST: Treatment for Childhood Apraxia of Speech

Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

Rheumatoid Arthritis Trials in Other Cities

A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)

Improving Self-Care of Behavioral Variant Frontotemporal Dementia Caregivers

A Safety Trial of Lisocabtagene Maraleucel (JCAR017) for Relapsed and Refractory (R/R) B-cell Non-Hodgkin Lymphoma (NHL) in the Outpatient Setting (TRANSCEND-OUTREACH-007)

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

Myeloma-Developing Regimens Using Genomics (MyDRUG)

Administration of Hydroxychloroquine (Plaquenil) to African Americans and Hispanics for the Treatment of Mild to Severe Ulcerative Colitis

Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia

ViBone in Cervical and Lumbar Spine Fusion

A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

Trial to Assess Safety and Efficacy of MOR202 in Anti-PLA2R + Membranous Nephropathy (aMN)

A Study to Evaluate the Efficacy and Safety of TNX-1900 in Patients With Chronic Migraine

A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers

Long-term Follow-up of Participants With Cerebral Adrenoleukodystrophy Who Were Treated With Lenti-D Drug Product

Persona Partial Knee Clinical Outcomes Study

An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

An International Multicenter Study on Transcatheter Device Closure of Perimembranous Ventricular Septal Defects

Other Conditions in Philadelphia