1. Significant stress incontinence or mixed stress/urge incontinence where stress is the predominant factor.

2. Urinary tract infection (UTI) within past 30 days, or history of recurrent UTI.

3. Hematuria associated with bladder malignancy or other significant pathology.

4. Had surgical procedure that affected bladder function.

5. Received intravesical therapy within past 12 months or had bladder hydrodistention within past 6 months.

6. Grade III/IV pelvic organ prolapse with/without cystocele or urethral diverticulum.

7. Clinically significant kidney disease or nephrolithiasis.

Study of V117957 in Overactive Bladder Syndrome