Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 1121-1140 of 3,347 trials

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

NCT04113434

The overall goal of the study is to risk stratify pediatric Acute Respiratory Distress Syndrome (ARDS) patients and to identify sub-phenotypes with shared biology in order to appropriately target therapies in future trials. This is a prospective, multicenter study of 500 intubated children with ARDS, with planned blood collection within 24 hours of ARDS onset and subsequent measurement of plasma protein biomarkers and peripheral blood gene expression.

Acute Respiratory Distress Syndrome

Children's Hospital of Philadelphia500 participantsStarted Jan 2020

Little Rock, Arkansas, United States • Aurora, Colorado, United States • Miami, Florida, United States +13 more locations

COMPLETEDPhase 2< 1 mile

Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

NCT02566304

This clinical trial studies the use of reduced intensity chemotherapy and radiation therapy before donor stem cell transplant in treating patients with hematologic malignancies. Giving low doses of chemotherapy, such as cyclophosphamide and fludarabine phosphate, before a donor stem cell transplant may help stop the growth of cancer cells. It may also stop the patient's immune system from rejecting the donor's stem cells. The donated stem cells may replace the patient's immune cells and help destroy any remaining cancer cells (graft-versus-tumor effect). Reducing the intensity of the chemotherapy and radiation may also reduce the side effects of the donor stem cell transplant.

Acute Myeloid LeukemiaAcute Myeloid Leukemia in RemissionAplastic Anemia+12 more

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University35 participantsStarted Nov 2015

Philadelphia, Pennsylvania, United States

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Rheumatoid Arthritis Trials in Other Cities

Traumatic Hemothorax Drainage and Daily Lavage: Pilot Study

A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation

A Study to Evaluate Rozanolixizumab in Study Participants With Generalized Myasthenia Gravis

Extracorporeal Photopheresis for Medicare Recipients of Lung Allografts

Neuromotor Prosthetic to Treat Stroke-Related Paresis

Phase 2 Study of HL-009 Liposomal Gel to Treat Mild to Moderate Atopic Dermatitis

A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)

Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

DALY II USA/ MB-CART2019.1 for DLBCL

Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System

Comparative Study of Conventional MR Images With Synthetically Reconstructed MR Images of the Brain

Study of REM-422 in Patients With AML or Higher Risk MDS

Visualization of the STN and GPi for DBS

Prophylaxis and Treatment of COVID-19

Clinical Trial Readiness to Solve Barriers to Drug Development in FSHD

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)

Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA

Other Conditions in Philadelphia