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A Phase 3, Randomized, Double-Blind Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Subjects With Moderately to Severely Active Rheumatoid Arthritis Who Are on a Stable Background of Methotrexate (MTX) and Who Have an Inadequate Response to MTX (MTX-IR)
Conditions
Interventions
Placebo for Adalimumab
Adalimumab
+2 more
Locations
370
United States
Achieve Clinical Research, LLC /ID# 143136
Birmingham, Alabama, United States
AZ Arthritis and Rheum Assoc /ID# 143130
Mesa, Arizona, United States
SunValley Arthritis Center, Lt /ID# 143123
Peoria, Arizona, United States
Elite Clinical Studies, LLC /ID# 144881
Phoenix, Arizona, United States
AZ Arthritis and Rheum Researc /ID# 143080
Phoenix, Arizona, United States
AZ Arthritis and Rheum Researc /ID# 143121
Phoenix, Arizona, United States
Start Date
December 1, 2015
Primary Completion Date
October 27, 2017
Completion Date
September 30, 2027
Last Updated
August 5, 2025
NCT07536529
NCT06329401
NCT07048197
NCT07484243
NCT06647069
NCT06841562
Lead Sponsor
AbbVie
Data Source & Attribution
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