Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 221-240 of 3,347 trials

Mechanistic Clinical Trial of Colchicine in Patients With Peripheral Artery Disease

NCT06212271

The goal of this mechanistic clinical trial is to test the effects of reducing inflammatory signaling in femoral artery atherosclerotic plaques. Researchers will compare patients receiving colchicine to patients receiving placebo to determine the effect of colchicine on the inflammatory state of atherosclerotic femoral arteries.

Peripheral Artery Disease

University of Pennsylvania24 participantsStarted Sep 2024

Philadelphia, Pennsylvania, United States

RECRUITINGNA< 1 mile

A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors

NCT06541002

This research study is evaluating the efficacy of a novel self-administered digital application for improving sexual health outcomes, quality of life, and psychological distress in hematopoietic stem cell transplant survivors.

Sexual DysfunctionStem Cell Transplant ComplicationsBone Marrow Transplant Complications

Massachusetts General Hospital300 participantsStarted Jan 2025

Coral Gables, Florida, United States • Boston, Massachusetts, United States • Philadelphia, Pennsylvania, United States

RECRUITINGEARLY Phase 1< 1 mile

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

NCT04655404

This is a pilot study that will evaluate disease status in children that have been newly diagnosed high-grade glioma with TRK fusion. The evaluation will occur after 2 cycles of the medication (Larotrectinib) have been given. The study will also evaluate the safety of larotrectinib when given with chemotherapy in your children; as well as the safety larotrectinib when given post-focal radiation therapy.

High Grade GliomaDiffuse Intrinsic Pontine Glioma

Nationwide Children's Hospital15 participantsStarted Apr 2021

Aurora, Colorado, United States • Washington D.C., District of Columbia, United States • Chicago, Illinois, United States +18 more locations

Mechanistic Clinical Trial of Colchicine in Patients With Peripheral Artery Disease

A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

Rheumatoid Arthritis Trials in Other Cities

Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) Trial

Evolut™ EXPAND TAVR II Pivotal Trial

A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

Selinexor and Pacritinib in JAK Inhibitor-naïve MF Patients With Cytopenias

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Topical Ketotifen 0.25% for Secondary Vestibulodynia

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

Study of Long-Term Safety and Efficacy on Gene Therapy in Glycogen Storage Disease Type Ia

A Follow-up Study to Describe the Safety of Study Participants Who Received RSVPreF3 Maternal Vaccination (Any Dose) or Controls From Previous RSV MAT Studies During Any Pregnancy Conceived Post Vaccination/Control

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study

Other Conditions in Philadelphia