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Clareo Health | Multiple Sclerosis Clinical Trials in Philadelphia | 137 Studies

Clinical Trials Multiple SclerosisPhiladelphia

Multiple Sclerosis Clinical Trials in Philadelphia

Find 137 clinical trials for multiple sclerosis near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Multiple Sclerosis trials nationwide All trials in Philadelphia

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 101-120 of 137 trials

CompletedTecfidera Lymphocyte Chart ReviewThe primary objective of the study is to retrospectively investigate changes in lymphocyte counts and lymphocyte subtypes, with a focus on CD4+ and CD8+ T cells, in participants…NCT02519413·Homewood, Alabama and 9 others CompletedSafety Study in Patients With Multiple Sclerosis Treated Fingolimod or Other Approved Disease-modifying TherapiesThe purpose of this world-wide prospective parallel-cohort study in patients with relapsing forms of MS, either newly treated with fingolimod or receiving another…NCT01442194·Birmingham, Alabama and 237 others

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Data from ClinicalTrials.govTerms

Active not recruitingSafety and Efficacy of Fingolimod in Pediatric Patients With Multiple SclerosisTo evaluate the safety and efficacy of fingolimod vs. interferon beta-1a i.m. in pediatric patients with multiple sclerosis (MS)NCT01892722·Birmingham, Alabama and 72 others

CompletedA Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving OcrelizumabThis study will evaluate the pharmacokinetics of ocrelizumab in the breastmilk of lactating women with clinically isolated syndrome (CIS) or multiple sclerosis (MS) \[in line with…NCT04998851·San Francisco, California and 7 others

CompletedGlatiramer Acetate (Copaxone®) Study to Follow Participants From the First Original Study for Safety and EffectivenessThis open-label extension study will evaluate the long-term safety of glatiramer acetate and its effect on the neurologic course of participants with relapsing-remitting multiple…NCT00203021·Los Angeles, California and 10 others

Active not recruitingLong-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MSThe purpose of this study is to collect long-term safety, tolerability, effectiveness and health outcomes data in eligible subjects who have participated in a Novartis ofatumumab…NCT03650114·Birmingham, Alabama and 294 others

UnknownImmunoregulatory Effect of Microparticle Delivered STING Agonist in the Control of Experimental Autoimmune Encephalomyelitis (EAE) and Multiple Sclerosis (MS)Microparticles (MPs) as a mode of therapeutic delivery can selectively deliver immunomodulatory treatment to the phagocytic cells, particularly dendritic cells (DCs), inducing…NCT05705986·Philadelphia, Pennsylvania

TerminatedMS Study Evaluating Safety and Efficacy of Two Doses of Fingolimod Versus CopaxoneThe purpose of this study was to demonstrate that at least one dose (0.5 mg followed by 0.25 mg) of fingolimod is superior to glatiramer acetate 20 mg SC in reducing the ARR up to…NCT01633112·Cullman, Alabama and 129 others

TerminatedEffect of MD1003 in Progressive Multiple Sclerosis (SPI2)The purpose of this study is to demonstrate the superiority of MD1003 over placebo in the disability of patients suffering from progressive multiple sclerosis and especially those…NCT02936037·Phoenix, Arizona and 91 others

CompletedEfficacy and Safety of BIIB019 (Daclizumab High Yield Process) Versus Interferon β 1a in Participants With Relapsing-Remitting Multiple SclerosisThe primary study objective is to test the superiority of Daclizumab High Yield Process (DAC HYP) compared to interferon β 1a (IFN β-1a) in preventing multiple sclerosis (MS)…NCT01064401·Gilbert, Arizona and 227 others

CompletedOne Year, Open Label, Dose Escalation Long-term Safety Study in Multiple Sclerosis (MS) Subjects With SpasticityClinical protocol OS440-3003 is a multicenter, open-label, non-randomized, uncontrolled, dose escalation study to evaluate the safety and tolerability of Arbaclofen Extended…NCT01844232·Gilbert, Arizona and 34 others

CompletedExploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND)Evaluate the safety and efficacy of Siponimod (BAF312) versus placebo in a variable treatment duration in patients with secondary progressive multiple sclerosis (Core Part)…NCT01665144·Phoenix, Arizona and 289 others

CompletedMeasuring Signatures in the Fluid Surrounding the Spinal Cord in Patients Who Have Problems With Intrathecal Drug DeliveryThe purpose of this study is to record signatures from the fluid surrounding the spinal cord from people who have an implanted drug infusion system.NCT01117090·Indianapolis, Indiana and 1 other

CompletedA Study To Investigate The Pharmacokinetics, Safety, And Tolerability Of Subcutaneous Ocrelizumab Administration In Participants With Multiple SclerosisThis study will evaluate the pharmacokinetics, safety and tolerability, and immunogenicity of ocrelizumab administered subcutaneously to participants with multiple sclerosis (MS).NCT03972306·Aurora, Colorado and 17 others

CompletedAllogenic Mesenchymal Stem Cells And Physical Therapy for MS TreatmentThis study aims at expanding Umbilical Cord derived Mesenchymal Stem Cells (MSCs) to a clinical scale according to Good Laboratory Practice and study its efficacy when compared to…NCT03326505·Amman and 1 other

TerminatedPhase 2 Extension Trial in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS)The objective of this active-drug Extension Study is to evaluate the continuing safety and efficacy of ONO-4641 (MSC2430913A) in subjects with relapsing-remitting multiple…NCT01226745·Tucson, Arizona and 69 others

Active not recruitingEfficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple SclerosisThe purpose of each study is to independently measure the annualized relapse rate (ARR) with administration of frexalimab compared to a daily oral dose of teriflunomide in male…NCT06141473·Birmingham, Alabama and 381 others

RecruitingBest Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell…NCT04047628·Palo Alto, California and 22 others

CompletedA Study of the Safety and Efficacy of ONO-4641 in Patients With Relapsing-Remitting Multiple SclerosisThe objective of this study is to evaluate the safety and efficacy of ONO-4641 in patients with relapsing-remitting multiple sclerosis over a 26-week treatment period.NCT01081782·Tucson, Arizona and 85 others

CompletedEfficacy and Safety Study of Ozanimod in Relapsing Multiple SclerosisThis study is a two-part trial consisting of Part A (see NCT01628393) and Part B, presented within this record.NCT02047734·Phoenix, Arizona and 298 others

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