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Clareo Health | Multiple Sclerosis Clinical Trials in Philadelphia | 137 Studies

Clinical Trials Multiple SclerosisPhiladelphia

Multiple Sclerosis Clinical Trials in Philadelphia

Find 137 clinical trials for multiple sclerosis near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Multiple Sclerosis trials nationwide All trials in Philadelphia

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 21-40 of 137 trials

Active not recruitingA Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS)This double-blind, double-dummy study will evaluate the safety and efficacy of ocrelizumab compared with fingolimod in children and adolescents with RRMS aged between 10 and \< 18…NCT05123703·La Jolla, California and 70 others

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Data from ClinicalTrials.govTerms

CompletedBRAVO Study: Laquinimod Double-blind Placebo-controlled Study in Participants With Relapsing-Remitting Multiple Sclerosis (RRMS) With a Rater Blinded Reference Arm of Interferon β-1a (Avonex®)The study aims to compare the effect of daily oral treatment of laquinimod capsules 0.6 milligrams (mg) with the effect of placebo capsules (capsules that contain no active…NCT00605215·Birmingham, Alabama and 169 others

CompletedFirst-in-Human Trial in Healthy Adult Volunteers to Evaluate Safety, Tolerability and PK of LAPIX Study Drug; LPX-TI641A Phase I First-in-Human, Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adult Volunteers to Evaluate Safety, Tolerability, and Pharmacokinetics after Single and…NCT05853835·Dilworth, Minnesota and 1 other

Enrolling by invitationPhysiological Effects of N-Acetyl Cysteine in Patients With Multiple SclerosisMultiple Sclerosis (MS) is a disease in which the myelin surrounding the nerve cells is damaged which affects functioning.NCT03032601·Philadelphia, Pennsylvania

CompletedStudy to Assess the Effect of Ofatumumab in Treatment Naïve, Very Early RRMS Patients Benchmarked Against Healthy Controls.This study evaluates the impact of ofatumumab in Relapsing Remitting Multiple Sclerosis (RRMS) participants that are very early in the course of their disease using clinical and…NCT05084638·Chandler, Arizona and 35 others

UnknownDeficient T Regulatory Cell (Treg) Function in Patients With Relapsing Remitting Multiple SclerosisThe purpose of this research is to find out how the T regulatory (Treg) cells control autoimmune response in multiple sclerosis.NCT04857489·Philadelphia, Pennsylvania

No longer availableExpanded Access Program for Ocrelizumab in Participants With Primary Progressive Multiple SclerosisThe primary objective of this expanded access program is to provide ocrelizumab as treatment for eligible participants with primary progressive multiple sclerosis (PPMS) before it…NCT02807285·Phoenix, Arizona and 55 others

CompletedLong Term Study of Avonex Therapy Following a First Attack of Multiple SclerosisThe current study is a continuation of the 5 year extension study of the phase III CHAMPS study (see reference).NCT00179478·Derby, Connecticut and 25 others

CompletedTreatment of Multiple Sclerosis Using Over the Counter InosineThe purpose of this study is to determine whether raising low levels of the natural antioxidant uric acid by the administration of a precursor, inosine, has any therapeutic effect…NCT00067327·Philadelphia, Pennsylvania

CompletedAdherence in Pediatric Multiple SclerosisDisease modifying therapies (DMT) are widely used for children and adolescents with MS. Nonetheless, many pediatric patients continue to relapse and therefore require changes in…NCT02234713·Birmingham, Alabama and 12 others

CompletedA Safety and Efficacy Study of ADS-5102 in Patients With Multiple Sclerosis and Walking ImpairmentThis study assessed the long-term safety and tolerability of ADS-5102 in subjects with MS and walking impairment who had completed the double-blind, placebo-controlled study of…NCT03567057·Cullman, Alabama and 91 others

CompletedOpen-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple SclerosisThe purpose of this study is to evaluate the long-term safety, tolerability and activity of Fampridine-SR in subjects with multiple sclerosis who have previously participated in…NCT00654927·Phoenix, Arizona and 21 others

TerminatedStudy of Evobrutinib in Participants With RMS (evolutionRMS 2)The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio®), administered orally once daily in participants…NCT04338061·Cullman, Alabama and 277 others

CompletedA Study of Ocrelizumab in Comparison With Interferon Beta-1a (Rebif) in Participants With Relapsing Multiple SclerosisThis randomized, double-blind, double-dummy, parallel-group study will evaluate the efficacy and safety of ocrelizumab in comparison with interferon beta-1a (Rebif) in…NCT01247324·Phoenix, Arizona and 141 others

CompletedStudy of Subcutaneous Daclizumab in Patients With Active, Relapsing Forms of Multiple SclerosisThis research study is being conducted in the U.S. and Europe to evaluate the safety and efficacy of daclizumab for the treatment of multiple sclerosis (MS).NCT00109161·Phoenix, Arizona and 35 others

TerminatedPhase 1/2 Study to Evaluate the Safety and Efficacy of ATA188 in Subjects With Progressive Multiple SclerosisThe purpose of this study is to evaluate the safety and tolerability of ATA188 as a monotherapy in Parts 1 and 2, to determine the recommended Part 2 dose (RP2D) of ATA188 as…NCT03283826·La Jolla, California and 30 others

CompletedSafety Study to Evaluate Immune Response of Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Ozanimod Compared to Non-Pegylated Interferon (IFN)-β or No Disease Modifying TherapyThis study is designed to provide data on the immune response and safety of administering vaccines to relapsing multiple sclerosis (RMS) participants taking ozanimod compared to…NCT05028634·Palo Alto, California and 32 others

CompletedNonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (HERCULES)Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in NRSPMS Secondary Objective: To evaluate efficacy of…NCT04411641·Birmingham, Alabama and 305 others

Active not recruitingA Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis PatientsForalumab is a human anti-CD3 monoclonal antibody being developed for the treatment of autoimmune and inflammatory diseases.NCT06292923·North Haven, Connecticut and 6 others

CompletedGentleCath™ for Men Intermittent Catheter With FeelClean™ TechnologyMale self catherterisng observational study.NCT05470751·West Orange, New Jersey and 15 others

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