SWOG-9430: Surgery in Treating Patients With Metastatic Melanoma

Inclusion Criteria

• •DISEASE CHARACTERISTICS:
• •Histologically confirmed metastatic melanoma that is deemed grossly surgically resectable
• •* Multiple resected sites or metastatic melanoma of unknown primary allowed provided all known disease can be grossly resected
• •* Recurrence in iliac lymph nodes after inguinal lymph dissection allowed
• •No metastatic disease beyond the lesions planned for resection
• •* Confirmed by CT scan of chest, abdomen, pelvis, and CT or MRI of brain within 42 days of study
• •Concurrent registration on protocol SWOG-9431 required
• •PATIENT CHARACTERISTICS:
• •Age:
• •18 and over
• •Performance status:
• •SWOG 0-2
• •Hematopoietic:
• •Not specified
• •Hepatic:
• •Not specified
• •Renal:
• •Not specified
• •Other:
• •No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix, or adequately treated stage I or II cancer from which patient is currently disease free
• •Not pregnant
• •PRIOR CONCURRENT THERAPY:
• •Biologic therapy:
• •Prior immunotherapy in the adjuvant or metastatic setting allowed
• •Chemotherapy:
• •Prior chemotherapy in the adjuvant or metastatic setting allowed
• •Endocrine therapy:
• •Prior hormonal therapy in the adjuvant or metastatic setting allowed
• •Radiotherapy:
• •Prior radiotherapy in the adjuvant or metastatic setting allowed
• •Surgery:
• •See Disease Characteristics
• •At least 14 days since prior surgery in the adjuvant or metastatic setting
• •Other:
• •Recovered from prior therapy