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Clareo Health | Melanoma Clinical Trials in Massachusetts | 361 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 361 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 21-40 of 361 trials

CompletedPhase 1 Safety and Tolerability of MEDI4736 in Combination With Dabrafenib and Trametinib or With Trametinib AloneThe purpose of this study is to determine the maximum tolerated dose and characterize the safety profile of durvalumab (MEDI4736) in combination with dabrafenib and trametinib or…NCT02027961·Scottsdale, Arizona and 10 others CompletedStudy of ILX651 in Patients With Inoperable Locally Advanced or Metastatic MelanomaThis is a Phase II, non-randomized, open label study of ILX651 in patients with inoperable locally advanced or metastatic melanoma.NCT00068211·Scottsdale, Arizona and 18 others

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Data from ClinicalTrials.govTerms

CompletedCarboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase III trial studies carboplatin, paclitaxel, and sorafenib tosylate to see how well they work compared to carboplatin and paclitaxel in treating patients with…NCT00110019·Birmingham, Alabama and 218 others

CompletedA Study of Vemurafenib in Metastatic Melanoma Participants With Brain MetastasesThis open-label, single-arm, multicenter study will evaluate the efficacy and safety in participants with metastatic melanoma who developed brain metastases.NCT01378975·Los Angeles, California and 32 others

TerminatedStudy of PF-07265807 in Participants With Metastatic Solid Tumors.A First-in-Human Pharmacokinetic, Safety, and Tolerability Study of PF-07265807 as Monotherapy and in Combination in Participants with Advanced or Metastatic Solid TumorsNCT04458259·Fayetteville, Arkansas and 32 others

CompletedA Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or ImmunotherapyThis research study is studying the changes in primary and metastatic brain tumor inflammation using positron emission tomography (PET) imaging using a radioactive substance…NCT02431572·Boston, Massachusetts and 1 other

CompletedPhase Ib/II Study of MCS110 in Combination With PDR001 in Patients With Advanced MalignanciesThe purpose of this study of MCS110 with PDR001 was to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of the…NCT02807844·Boston, Massachusetts and 19 others

TerminatedA Study of Varlilumab and Atezolizumab in Patients With Advanced CancerThis is a study to determine the clinical benefit (how well the drug works), safety and tolerability of combining varlilumab and atezolizumab.NCT02543645·San Francisco, California and 3 others

RecruitingNeoadjuvant Darovasertib in Primary Uveal MelanomaThis is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma (OptimUM-10)NCT07015190·Scottsdale, Arizona and 93 others

CompletedEvaluating The Antitumor Activity Of MEDI-522 With Or Without Dacarbazine In Patients With Metastatic MelanomaThe primary objectives of this study are: * To explore the antitumor activity of MEDI-522 ± DTIC in patients with metastatic melanoma.NCT00066196·Scottsdale, Arizona and 24 others

CompletedEnsuring Communication in Hospice by Oncology Study (ECHO)The goal of this study is to determine if scheduled communication with the oncology team through phone calls is helpful to caregivers with the transition to hospice care.NCT02069769·Boston, Massachusetts

TerminatedA Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced MelanomaThis study will examine the effectiveness and safety of glembatumumab vedotin as monotherapy or in combination with immunotherapies in patients with advanced melanoma.NCT02302339·Los Angeles, California and 13 others

CompletedA Study of DF6002 Alone and in Combination With NivolumabThe purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and in combination with Nivolumab…NCT04423029·Orange, California and 31 others

CompletedStudy of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV MelanomaThe primary goal of this study is to determine if people with metastatic melanoma who receive Heat Shock Protein-Peptide Complex - 96 (HSPPC-96 or Oncophage) after surgery live…NCT00039000·Birmingham, Alabama and 76 others

CompletedVaccine Therapy in Treating Patients With Stage IV MelanomaRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00033228·Tucson, Arizona and 4 others

CompletedA Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid TumorsThis research study is done to test how well different types of cancer respond to the drug called larotrectinib.NCT02576431·Palo Alto, California and 97 others

Active not recruitingA Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022.NCT02817633·Goodyear, Arizona and 88 others

TerminatedComparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic RadiosurgeryThis phase III trial compares the effect of adding whole brain radiotherapy with hippocampal avoidance and memantine versus stereotactic radiosurgery alone in treating patients…NCT04588246·Tucson, Arizona and 80 others

CompletedA Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With BRAFV600-Mutation Positive Metastatic MelanomaThis is an open-label, multicenter, Phase Ib, dose-escalation and cohort-expansion study of atezolizumab (anti-programmed death-ligand 1 \[PD-L1\] antibody) in combination with…NCT01656642·Los Angeles, California and 7 others

CompletedPhase I Clinical Trial of Tremelimumab Plus MEDI3617 in Patients With Unresectable Stage III or Stage IV MelanomaThis is an open label, phase I trial, testing the combination of Tremelimumab and MEDI3617 in patients with metastatic melanoma.NCT02141542·Boston, Massachusetts and 1 other

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