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Clareo Health | Melanoma Clinical Trials in Massachusetts | 363 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 363 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 261-280 of 363 trials

CompletedMCS110 With BRAF/MEK Inhibition in Patients With MelanomaThis research study is studying a combination of targeted therapies as a possible treatment for advanced melanoma that was found to have a BRAF V600E or BRAF V600K genetic…NCT03455764·Boston, Massachusetts RecruitingA Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant TumorsThis study will evaluate the safety, efficacy, optimal dose, and pharmacokinetics (PK) of BNT326 as monotherapy (Part 1) and as combination treatment with immunotherapeutic agents…NCT07070232·Phoenix, Arizona and 76 others

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Data from ClinicalTrials.govTerms

TerminatedCMP-001 in Combination With Nivolumab in Subjects With Advanced MelanomaCMP-001-010 is a Phase 2 study of CMP-001 intratumoral (IT) and nivolumab intravenous (IV) administered to participants with refractory unresectable or metastatic melanoma.NCT04698187·Phoenix, Arizona and 24 others

TerminatedTiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell TherapyTiTAN-1 is a first-in-human study of GEN-011, an experimental treatment being evaluated in adult patients with advanced cancer.NCT04596033·Gilbert, Arizona and 7 others

RecruitingA Phase 1 of CTX-8371 in Patients With Advanced MalignanciesThis is a Phase 1, open-label, first-in-human study of CTX-8371 administered as a monotherapy in patients with metastatic or locally advanced malignancies.NCT06150664·Birmingham, Alabama and 11 others

Active not recruitingHippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized TrialThis research study is studying two different types of radiation as treatment for brain metastases (tumors in the brain that spread from a cancer that originated elsewhere in the…NCT03075072·Boston, Massachusetts and 1 other

CompletedImmunotherapy With IFx-Hu2.0 Vaccine for Advanced Non-melanoma Skin CancersIn this clinical phase I, non-randomized, open-label, uncontrolled, interventional, multi-center trial, 20 adult subjects (≥ 18 years of age) with advanced non-melanoma skin…NCT04160065·Los Angeles, California and 3 others

CompletedGSK3359609 Plus Tremelimumab for the Treatment of Advanced Solid TumorsThe purpose of this study is to evaluate if the combination of GSK3359609 and tremelimumab is safe and tolerable (Part 1) and provides significant survival benefit to subjects…NCT03693612·Boston, Massachusetts and 7 others

CompletedPhase 3 Study of Nivolumab or Nivolumab Plus Ipilimumab Versus Ipilimumab Alone in Previously Untreated Advanced Melanoma (CheckMate 067)The purpose of this study is to show that Nivolumab and/or Nivolumab in combination with Ipilimumab will extend progression free survival and overall survival compared to…NCT01844505·Gilbert, Arizona and 149 others

TerminatedA Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal MelanomaA phase Ib dose-escalation study of the AEB071 and MEK162 combination in adult patients with confirmed metastatic uveal melanoma.NCT01801358·Boston, Massachusetts and 6 others

TerminatedA Study of MEK162 and AMG 479 in Patients With Selected Solid TumorsThis is a multi-center, open-label, phase Ib/II study.NCT01562899·Boston, Massachusetts and 8 others

CompletedSafety, Pharmacokinetics (PK) of AKT and MEK CombinationThis study is a Phase 1 dose-escalation open-label study to determine the recommended Phase II dose (RP2D) and regimen for the combination of the orally administered MEK inhibitor…NCT01138085·Aurora, Colorado and 9 others

CompletedA Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301)The purpose of the study is to assess the efficacy, safety, and tolerability when combining pembrolizumab with epacadostat or placebo in participants with unresectable or…NCT02752074·Birmingham, Alabama and 128 others

CompletedPAN-EU Utilization, Effectiveness and Safety of Ipilimumab Administered in EAP Patients With Advanced MelanomaObservational study to evaluate the effectiveness and safety of ipilimumab, administered during the European expanded access programme (EAP) in pretreated patients with advanced…NCT02492815·Boston, Massachusetts and 16 others

CompletedMelanoma Checkpoint and Gut Microbiome Alteration With Microbiome InterventionThis study is designed to evaluate the safety and tolerability of treatment with oral microbiome study intervention (SER-401) or matching placebo in combination with…NCT03817125·Los Angeles, California and 6 others

CompletedAn Investigational Immuno-therapy Study to Evaluate Safety and Effectiveness in Patients With Melanoma That Has Spread to the Brain, Treated With Nivolumab in Combination With Ipilimumab, Followed by Nivolumab by ItselfThis is a study of Nivolumab combined with Ipilimumab followed by Nivolumab by itself for the treatment of patients with Melanoma that has spread to the brain.NCT02320058·Duarte, California and 35 others

UnknownDose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid TumorsThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of escalating doses of RMC-4630 monotherapy in adult…NCT03634982·Scottsdale, Arizona and 11 others

TerminatedCombined BRAF-Targeted Therapy & Immunotherapy for MelanomaThis research study is a Phase II clinical trial of an investigational combination of drugs (vemurafenib and aldesleukin) to learn whether the combination works in treating a…NCT01754376·Boston, Massachusetts and 1 other

RecruitingTebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator…NCT05549297·Phoenix, Arizona and 81 others

CompletedA Study of IMMray™ PanCan-d Test for Early Detection of Pancreatic Cancer in High-risk GroupsPanFAM-1 is a clinical study for early detection of pancreatic cancer in high-risk groups.NCT03693378·Stanford, California and 20 others

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