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Clareo Health | Melanoma Clinical Trials in Massachusetts | 363 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 363 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 281-300 of 363 trials

TerminatedHigh-Risk Skin Cancers With Atezolizumab Plus NT-I7The purpose of this study is to test whether the addition of NT-I7 to atezolizumab provides clinically meaningful outcomes for patients with anti-PD-1/PD-L1 naive or…NCT03901573·Duarte, California and 7 others CompletedA Study to Evaluate Safety and Therapeutic Activity of RO6874281 in Combination with Pembrolizumab, in Participants with Advanced or Metastatic MelanomaThis is an open-label, multicenter, Phase Ib study to evaluate the safety and therapeutic activity of RO6874281 in combination with pembrolizumab.NCT03875079·New Haven, Connecticut and 22 others

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Data from ClinicalTrials.govTerms

CompletedEvaluation of Tumor Response to Ipilimumab in the Treatment of Melanoma With Brain MetastasesTo assess the response of melanoma with brain metastases to ipilimumab treatment while maintaining acceptable tolerability.NCT00623766·Scottsdale, Arizona and 13 others

CompletedPhase 1 Study of Intradermal LV305 in Patients With Locally Advanced, Relapsed or Metastatic Cancer Expressing NY-ESO-1This is a Phase 1 multi-center study to evaluate the clinical safety and immune response of ID-LV305 when injected intradermally in patients with advanced cancer.NCT02122861·San Francisco, California and 6 others

CompletedMDX-010 Antibody, MDX-1379 Melanoma Vaccine, or MDX-010/MDX-1379 Combination Treatment for Patients With Unresectable or Metastatic MelanomaThe purpose of this study is to determine the safety and efficacy of MDX-010 (ipilimumab, BMS-734016) (anti-CTLA4) in combination with MDX-1379 (gp100, BMS-734019) in patients…NCT00094653·Tucson, Arizona and 208 others

RecruitingSUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous MelanomaThis clinical trial is a prospective, multicenter, open-label, randomized, actively controlled, parallel-group Phase 3 clinical trial to evaluate the efficacy, safety and…NCT06743126·Phoenix, Arizona and 70 others

CompletedVaccine Trial for Clear Cell Sarcoma, Pediatric Renal Cell Carcinoma, Alveolar Soft Part Sarcoma and Children With Stage IV MelanomaThe purpose of this study is to learn if a vaccine made from the patient's own tumor cells, then genetically modified to secrete granulocyte-macrophage colony-stimulating factor…NCT00258687·Boston, Massachusetts and 1 other

CompletedEfficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV MelanomaThe purpose of this study is to determine whether nivolumab is better than ipilimumab to prevent recurrence of melanoma.NCT02388906·Little Rock, Arkansas and 135 others

RecruitingNeoadjuvant Darovasertib in Primary Uveal MelanomaThis is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma (OptimUM-10)NCT07015190·Scottsdale, Arizona and 93 others

TerminatedA Study to Investigate LYL845 in Adults With Solid TumorsThis is an open-label, multi-center, dose-escalation study with expansion cohorts, designed to evaluate the safety and anti-tumor activity of LYL845, an epigenetically…NCT05573035·Sacramento, California and 17 others

CompletedA Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)This is a Phase 1/2, open label study. Phase 1 consists of 2 parts.NCT02327078·Birmingham, Alabama and 23 others

CompletedAdoptive Transfer of MART1/Melan-A CTL for Malignant MelanomaRATIONALE: Cytotoxic T lymphocytes (CTL) are cells of the immune system that can fight infections and cancer.NCT00512889·Boston, Massachusetts

CompletedAn Expanded Cohort Trial of Bortezomib and Sorafenib in Advanced Malignant MelanomaThis research study involves the use of two investigational drugs: sorafenib and bortezomib.NCT01078961·Boston, Massachusetts and 2 others

RecruitingCollecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer DetectionThis study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.NCT05334069·Anchorage, Alaska and 750 others

TerminatedStudy of ASN003 in Subjects With Advanced Solid TumorsThe study is divided into two parts. The first part of the study will test various doses of ASN003 to find out the highest safe dose to test in three specific groups.NCT02961283·Los Angeles, California and 4 others

CompletedInterferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the GroinRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Interferon alfa-2b may interfere with the growth of cancer cells.NCT00003444·Atlanta, Georgia and 22 others

UnknownIntensity-Modulated or Proton Radiation Therapy for Sinonasal MalignancyThe purpose of this study is to test the hypothesis that 1)intensity-modulated radiotherapy (IMRT) or proton radiation therapy would result in improved local control rate and…NCT01586767·Boston, Massachusetts and 1 other

CompletedA Study of Vemurafenib in Metastatic Melanoma Participants With Brain MetastasesThis open-label, single-arm, multicenter study will evaluate the efficacy and safety in participants with metastatic melanoma who developed brain metastases.NCT01378975·Los Angeles, California and 32 others

CompletedSafety Study Using Photodynamic Therapy Light Therapy for Patients With Chest Wall Progression of Breast Cancer and Satellite Metastases of MelanomaThis research is intended to explore a new approach to therapy when breast cancer recurs in the skin.NCT00862901·Boston, Massachusetts

RecruitingA Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid TumorsThis is a Phase 1/2a, open-label, study to evaluate the safety and preliminary efficacy of intratumoral T3011 given alone and in combination with intravenous pembrolizumab in…NCT04370587·Gilbert, Arizona and 8 others

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