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Clareo Health | Melanoma Clinical Trials in Massachusetts | 361 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 361 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 241-260 of 361 trials

TerminatedPhase I-Ib/II Study of MBG453 as Single Agent and in Combination With PDR001 in Patients With Advanced MalignanciesThe purpose of this first-in-human study of MBG453 was to characterize the safety, tolerability, pharmacokinetics, pharmacodynamics and anti-tumor activity of MBG453 administered…NCT02608268·Baltimore, Maryland and 13 others CompletedCAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumorsNCT03504488·Tucson, Arizona and 58 others

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Data from ClinicalTrials.govTerms

CompletedSafety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerThe purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Keytruda (pembrolizumab) when given to patients with B7-H3-expressing melanoma…NCT02475213·Scottsdale, Arizona and 19 others

CompletedDasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By SurgeryRATIONALE: Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00700882·Little Rock, Arkansas and 152 others

Active not recruitingA Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07799933) administered as a single agent and in combination with other…NCT05355701·Fayetteville, Arkansas and 39 others

UnknownBoron Neutron Capture Therapy in Treating Patients With Stage III MelanomaRATIONALE: Boron neutron capture therapy may selectively kill tumor cells without harming normal tissue.NCT00002781·Boston, Massachusetts and 1 other

CompletedPROCLAIM Registry to Evaluate the Treatment Patterns and Clinical Response in MalignancyThe purpose of this registry is to collect information on patients who are receiving treatment with Proleukin in an organized way, and to learn more about patient care during and…NCT01415167·Tucson, Arizona and 44 others

Active not recruitingTesting Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has SpreadThis phase II trial compares the effect of dabrafenib and trametinib given continuously to given with a break in treatment (intermittent) in treating patients with stage III-IV…NCT02196181·Birmingham, Alabama and 751 others

Active not recruitingNeoantigen Vaccine Plus Locally Administered Ipilimumab and Systemic Nivolumab in Advanced MelanomaThis research study is investigating a new type of personalized neoantigen vaccine, NeoVax, plus Montanide® in combination with Ipilimumab (Yervoy™) and Nivolumab (Opdivo®) as a…NCT03929029·Boston, Massachusetts

TerminatedThe Effects of Vemurafenib + Cobimetinib on Immunity in Patients With MelanomaThis study is for patients with malignant melanoma which has spread beyond the local area and cannot be surgically removed, and who have melanoma tumors that are accessible for…NCT01813214·Washington D.C., District of Columbia and 3 others

WithdrawnNivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal MelanomaThis randomized phase II trial studies how well nivolumab or expectant observation following ipilimumab, nivolumab, and surgery work in treating patients with high-risk mucosal…NCT03220009·Boston, Massachusetts

RecruitingA Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal MelanomaThe purpose of this study is to measure the clinical benefits of the combination of RP2 and nivolumab as compared with the combination of nivolumab and ipilimumab in patients with…NCT06581406·Scottsdale, Arizona and 32 others

TerminatedA Study of LY3009120 in Participants With Advanced Cancer or Cancer That Has Spread to Other Parts of Their BodyThe main purpose of this study is to see how safe the investigational drug known as LY3009120 is and whether it will work to help people with advanced cancer or cancer that has…NCT02014116·Scottsdale, Arizona and 5 others

CompletedSafety Study of MGA271 in Refractory CancerThe purpose of this study is to evaluate the safety of MGA271 when given by intravenous (IV) infusion to patients with refractory cancer.NCT01391143·Los Angeles, California and 11 others

CompletedGlycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemiplimab.NCT05259696·La Jolla, California and 12 others

TerminatedDinaciclib in Treating Patients With Stage III-IV MelanomaThis is a phase I/II trial is studying the side effects and best dose of dinaciclib and to see how well it works in treating patients with advanced melanoma.NCT01026324·Boston, Massachusetts

CompletedA Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid TumorsThe purpose of this study is to evaluate the safety and tolerability of CFT1946 as well as to determine the maximum tolerated dose (MTD) and/or the recommended Phase 2 dose (RP2D)…NCT05668585·Tucson, Arizona and 25 others

TerminatedSafety Study of High Dose Temozolomide to Treat Relapsed/Refractory Central Nervous System (CNS) MalignancyThe goal of this study is to find the maximum dose of a drug, temozolomide, that can safely be given to subjects with brain tumors.NCT00629187·Boston, Massachusetts

CompletedMCS110 With BRAF/MEK Inhibition in Patients With MelanomaThis research study is studying a combination of targeted therapies as a possible treatment for advanced melanoma that was found to have a BRAF V600E or BRAF V600K genetic…NCT03455764·Boston, Massachusetts

CompletedA Study to Evaluate Safety and Therapeutic Activity of RO6874281 in Combination with Pembrolizumab, in Participants with Advanced or Metastatic MelanomaThis is an open-label, multicenter, Phase Ib study to evaluate the safety and therapeutic activity of RO6874281 in combination with pembrolizumab.NCT03875079·New Haven, Connecticut and 22 others

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