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Clareo Health | Melanoma Clinical Trials in Massachusetts | 361 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 361 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 221-240 of 361 trials

TerminatedStudy of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid TumorsA prospective, open-label, multi-cohort, non-randomized, multicenter Phase 2 study evaluating adoptive cell therapy (ACT) with TIL \[LN-144/LN-145 (lifileucel)\] in combination…NCT03645928·La Jolla, California and 33 others

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Data from ClinicalTrials.govTerms

RecruitingVideo Education With Result Dependent dIsclosureThe overall study objective of this trial study is to identify and evaluate strategies to improve the accessibility of the video education with result dependent disclosure (VERDI)…NCT05225428·Boston, Massachusetts

RecruitingInterleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV MelanomaThis study will evaluate how safe the study drug is, how well patients tolerate it, how it works in the body, and the disease's response to the drug.NCT05428007·Los Angeles, California and 3 others

CompletedTrametinib in Treating Patients With Advanced Melanoma With BRAF Non-V600 MutationsThis phase II trial studies trametinib in treating patients with melanoma with v-Raf murine sarcoma viral oncogene homolog B (BRAF) non-V600 mutations that has spread to other…NCT02296112·Washington D.C., District of Columbia and 3 others

CompletedA Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic TumorsThis is a Phase 1a/1b, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, immune response, and pharmacokinetics of autogene…NCT03289962·Scottsdale, Arizona and 32 others

Active not recruitingA Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersThe purpose of this study is to characterize the safety and tolerability of KFA115 and KFA115 in combination with pembrolizumab in patients with select advanced cancers, and to…NCT05544929·Boston, Massachusetts and 18 others

CompletedA Study to Evaluate RAF265, an Oral Drug Administered to Subjects With Locally Advanced or Metastatic MelanomaThe purpose of this study is to determine the safety profile, pharmacokinetics, pharmacodynamics and maximum tolerated dose of RAF265 in patients with locally advanced and…NCT00304525·Aurora, Colorado and 10 others

Enrolling by invitationGenetic Risk Stratification of Pediatric Skin LesionsA study to understand the clinical utility of noninvasive adhesive skin biopsies in pediatric patients by exploring whether DermTech Pigmented Lesion Assay (PLA) genetic risk…NCT05418959·Boston, Massachusetts

CompletedA Phase 1b/2a Study Evaluating AMG 232 in Metastatic MelanomaPhase 1b/2a, open-label, sequential dose escalation and expansion study of AMG 232 in combination with trametinib and dabrafenib in subjects with metastatic melanoma followed by a…NCT02110355·Los Angeles, California and 6 others

TerminatedTrial of Vemurafenib/Cobimetinib With or Without Bevacizumab in Patients With Stage IV BRAFV600 Mutant MelanomaThis phase 2 clinical trial randomizes patients with BRAF mutant melanoma to either (1) standard of care (SOC) - BRAF inhibitor vemurafenib in combination with MEK inhibitor…NCT01495988·Los Angeles, California and 13 others

RecruitingA Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory MelanomaThe goal of this clinical trial is to understand if a new drug called LNS8801 can safely treat patients with melanoma.NCT06624644·Newport Beach, California and 8 others

UnknownVaccine Therapy in Treating Patients Who Have Stage II, Stage III, or Stage IV MelanomaRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00010309·Boston, Massachusetts and 2 others

RecruitingPhase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable TumorsThis is a multicenter, multi-arm trial evaluating anti-tumor activity, safety, and immune infiltration of IO102-IO103 in combination with pembrolizumab KEYTRUDA® as neoadjuvant…NCT05280314·New Haven, Connecticut and 14 others

TerminatedHigh-Dose Aldesleukin and Ipilimumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed By SurgeryThis phase II trial studies how well high-dose aldesleukin and ipilimumab works in treating patients with stage III-IV melanoma that cannot be removed by surgery.NCT02203604·Maywood, Illinois and 5 others

Active not recruitingBasket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors that harbor an NTRK1/2/3, ROS1, or ALK…NCT02568267·Phoenix, Arizona and 119 others

CompletedA Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant MelanomaThe main purpose of this research study is to compare the safety, tolerability, and anti tumor activity of an investigational drug, ABI-007 versus Dacarbazine in patients with…NCT00864253·Birmingham, Alabama and 111 others

CompletedA Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid TumorsIn this four-part study, NKTR-214 was administered in combination with nivolumab and with/without other anticancer therapies.NCT02983045·La Jolla, California and 57 others

UnknownVaccine Therapy for Patients With Stage IV MelanomaThis is a Phase III study in patients with melanoma that has spread to the lymph nodes and/or a distant organ, and who have had all of their cancer surgically removed.NCT00052156·Tucson, Arizona and 76 others

RecruitingA Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor MalignanciesThis is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of…NCT05669430·Los Angeles, California and 12 others

CompletedA Study of the Effects of ALKS 4230 (Nemvaleukin Alfa) on Subjects With Solid TumorsTo better understand the safety and tolerability of ALKS 4230 in humansNCT02799095·Denver, Colorado and 30 others

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