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Clareo Health | Melanoma Clinical Trials in Boston | 355 Studies

Clinical Trials MelanomaBoston

Melanoma Clinical Trials in Boston

Find 355 clinical trials for melanoma near Boston, Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Boston

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

Healthy volunteers too

Showing 81-100 of 355 trials

Active not recruitingPhysician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by SurgeryThis randomized phase III trial studies how well pembrolizumab works compared with the current standard of care, physician/patient choice of either high-dose recombinant…NCT02506153·Birmingham, Alabama and 575 others

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Data from ClinicalTrials.govTerms

CompletedRTA 408 Capsules in Patients With Melanoma - REVEALMalignant melanoma is a leading cause of death from cutaneous malignancies, accounting for approximately three-fourths of all skin cancer deaths.NCT02259231·Mobile, Alabama and 9 others

CompletedEfficacy and Safety Study of Talimogene Laherparepvec Compared to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in MelanomaThe objective of this study is to evaluate the efficacy and safety of treatment with talimogene laherparepvec compared to subcutaneously administered GM-CSF in patients with…NCT00769704·Tucson, Arizona and 82 others

Active not recruitingEffectiveness Study of Nivolumab Compared to Placebo in Prevention of Recurrent Melanoma After Complete Resection of Stage IIB/C MelanomaThe purpose of this study is to determine the effectiveness of nivolumab adjuvant immunotherapy compared to placebo in adults and pediatric participants after complete resection…NCT04099251·Birmingham, Alabama and 129 others

CompletedStudy Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566To assess the safety and tolerability at increasing dose levels of PF-04518600 alone or in combination wtih PF-05082566 in patients with select advanced or metastatic carcinoma in…NCT02315066·Los Angeles, California and 29 others

Enrolling by invitationTruScore Standalone Clinical StudyThe goal of this clinical trial is to evaluate if the TruScore device can accurately diagnose suspicious skin lesions in patients aged 22 years and older.NCT06793423·Pleasanton, California and 5 others

WithdrawnA Phase II Trial of Neoadjuvant Treatment With PD-1 Inhibition (Nivolumab) With or Without IDO Inhibition (BMS-986205) and With or Without CTLA-4 Inhibition (Ipilimumab) in Resectable Stage III or IV MelanomaThis research study is studying different immunotherapy regimens as a possible treatment for stage III or IV resectable melanoma.NCT04007588·Boston, Massachusetts and 1 other

CompletedThe Use of Dendritic Cell/Tumor Hybridomas as a Novel Tumor Vaccine in Patients With Advance MelanomaThis study aims to determine if the vacccine can be used safely in patients with advanced melanoma (cancer of the pigment cells) and whether the cells in this vaccine are capabale…NCT00626860·Boston, Massachusetts

TerminatedStudy of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck CancerThis is a first-in-human, open-label, nonrandomized, four-part trial to determine the safety profile and identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose…NCT03809624·Scottsdale, Arizona and 22 others

Active not recruitingA Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic MelanomaThe purpose of this study is to learn about the effects of three study medicines (encorafenib, binimetinib, and pembrolizumab) given together for the treatment of melanoma…NCT04657991·Orlando, Florida and 150 others

CompletedS0008: Chemotherapy Plus Biological Therapy in Treating Patients With MelanomaRATIONALE: Interferon alfa may interfere with the growth of cancer cells.NCT00006237·Birmingham, Alabama and 296 others

TerminatedDose Finding Study of TNO155 in Adult Patients With Advanced Solid TumorsThe purpose of this first in human (FIH) trial was to characterize the safety and tolerability of the SHP2 inhibitor TNO155 alone and in combination with EGF816 (nazartinib) and…NCT03114319·Tampa, Florida and 17 others

TerminatedStudy of PF-07265807 in Participants With Metastatic Solid Tumors.A First-in-Human Pharmacokinetic, Safety, and Tolerability Study of PF-07265807 as Monotherapy and in Combination in Participants with Advanced or Metastatic Solid TumorsNCT04458259·Fayetteville, Arkansas and 32 others

CompletedClinical Study of CMP-001 in Combination With Pembrolizumab or as a MonotherapyThis study will be conducted in two parts: Part 1 will be conducted using a Dose Escalation and Expansion design.NCT02680184·Phoenix, Arizona and 12 others

CompletedEnapotamab Vedotin (HuMax-AXL-ADC) Safety Study in Patients With Solid TumorsThe purpose of the trial is to determine the maximum tolerated dose and to establish the safety profile of HuMax-AXL-ADC in a mixed population of patients with specified solid…NCT02988817·Phoenix, Arizona and 40 others

CompletedA Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid TumorsThe purpose of this study is to evaluate the safety and tolerability of CFT1946 as well as to determine the maximum tolerated dose (MTD) and/or the recommended Phase 2 dose (RP2D)…NCT05668585·Tucson, Arizona and 25 others

Active not recruitingADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)This study will investigate the safety and tolerability of ADP-A2M4CD8 T-cell therapy in subjects who have the appropriate human leukocyte antigen (HLA) and MAGE-A4 tumor antigen.NCT04044859·Orlando, Florida and 16 others

TerminatedPhase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1This is a Phase 1b, open label, multi-center study of CMB305 (sequentially administered LV305 \[a dendritic cell-targeting viral vector expressing the NY-ESO-1 gene\] and G305…NCT02387125·Santa Monica, California and 7 others

Active not recruitingUse of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment DiscontinuationThe goal of this prospective study to investigate the use of circulating tumor DNA (ctDNA) to guide end of therapy decisions in patients with melanoma or non-small-cell lung…NCT06146920·Boston, Massachusetts

Active not recruitingA Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With SurgeryThis study is researching an experimental drug called REGN3767, also known as fianlimab (R3767), when combined with another medication called cemiplimab (each individually called…NCT05608291·La Jolla, California and 210 others

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