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Clareo Health | Melanoma Clinical Trials in Boston | 355 Studies

Clinical Trials MelanomaBoston

Melanoma Clinical Trials in Boston

Find 355 clinical trials for melanoma near Boston, Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Boston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 281-300 of 355 trials

RecruitingSUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous MelanomaThis clinical trial is a prospective, multicenter, open-label, randomized, actively controlled, parallel-group Phase 3 clinical trial to evaluate the efficacy, safety and…NCT06743126·Phoenix, Arizona and 70 others

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Data from ClinicalTrials.govTerms

CompletedVaccine Trial for Clear Cell Sarcoma, Pediatric Renal Cell Carcinoma, Alveolar Soft Part Sarcoma and Children With Stage IV MelanomaThe purpose of this study is to learn if a vaccine made from the patient's own tumor cells, then genetically modified to secrete granulocyte-macrophage colony-stimulating factor…NCT00258687·Boston, Massachusetts and 1 other

CompletedEfficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV MelanomaThe purpose of this study is to determine whether nivolumab is better than ipilimumab to prevent recurrence of melanoma.NCT02388906·Little Rock, Arkansas and 135 others

RecruitingNeoadjuvant Darovasertib in Primary Uveal MelanomaThis is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma (OptimUM-10)NCT07015190·Scottsdale, Arizona and 93 others

TerminatedA Study to Investigate LYL845 in Adults With Solid TumorsThis is an open-label, multi-center, dose-escalation study with expansion cohorts, designed to evaluate the safety and anti-tumor activity of LYL845, an epigenetically…NCT05573035·Sacramento, California and 17 others

CompletedA Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)This is a Phase 1/2, open label study. Phase 1 consists of 2 parts.NCT02327078·Birmingham, Alabama and 23 others

CompletedAdoptive Transfer of MART1/Melan-A CTL for Malignant MelanomaRATIONALE: Cytotoxic T lymphocytes (CTL) are cells of the immune system that can fight infections and cancer.NCT00512889·Boston, Massachusetts

CompletedAn Expanded Cohort Trial of Bortezomib and Sorafenib in Advanced Malignant MelanomaThis research study involves the use of two investigational drugs: sorafenib and bortezomib.NCT01078961·Boston, Massachusetts and 2 others

RecruitingCollecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer DetectionThis study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.NCT05334069·Anchorage, Alaska and 750 others

TerminatedStudy of ASN003 in Subjects With Advanced Solid TumorsThe study is divided into two parts. The first part of the study will test various doses of ASN003 to find out the highest safe dose to test in three specific groups.NCT02961283·Los Angeles, California and 4 others

CompletedInterferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the GroinRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Interferon alfa-2b may interfere with the growth of cancer cells.NCT00003444·Atlanta, Georgia and 22 others

UnknownIntensity-Modulated or Proton Radiation Therapy for Sinonasal MalignancyThe purpose of this study is to test the hypothesis that 1)intensity-modulated radiotherapy (IMRT) or proton radiation therapy would result in improved local control rate and…NCT01586767·Boston, Massachusetts and 1 other

CompletedA Study of Vemurafenib in Metastatic Melanoma Participants With Brain MetastasesThis open-label, single-arm, multicenter study will evaluate the efficacy and safety in participants with metastatic melanoma who developed brain metastases.NCT01378975·Los Angeles, California and 32 others

CompletedSafety Study Using Photodynamic Therapy Light Therapy for Patients With Chest Wall Progression of Breast Cancer and Satellite Metastases of MelanomaThis research is intended to explore a new approach to therapy when breast cancer recurs in the skin.NCT00862901·Boston, Massachusetts

RecruitingA Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid TumorsThis is a Phase 1/2a, open-label, study to evaluate the safety and preliminary efficacy of intratumoral T3011 given alone and in combination with intravenous pembrolizumab in…NCT04370587·Gilbert, Arizona and 8 others

Active not recruitingDinaciclib in Treating Patients With Stage IV MelanomaThis phase II trial is studying the side effects and how well dinaciclib works in treating patients with stage IV melanoma.NCT00937937·Mobile, Alabama and 189 others

CompletedA Study of Vemurafenib in Previously Treated Patients With Metastatic MelanomaThis open-label single arm study will assess the efficacy, safety and tolerability of Vemurafenib in previously treated patients with metastatic melanoma.NCT00949702·Los Angeles, California and 14 others

Active not recruitingIDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal MelanomaThis is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be…NCT05987332·Scottsdale, Arizona and 67 others

Active not recruitingSafety and Tolerability of IPH4502 in Patients With Advanced Solid TumorsThis is a first-in-human, open-label, multicenter, Phase 1 study to evaluate the safety, tolerability and preliminary efficacy of IPH4502 and to determine the recommended Phase 2…NCT06781983·Boston, Massachusetts and 6 others

Active not recruitingNeoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in MelanomaThe purpose of this study is to test the effects of anti-PI-1 inhibitor (TSR-042) or anti-PD-1/anti-TIM-3 combination (TSR-042 / TSR-022) in patients with operable melanoma.NCT04139902·Washington D.C., District of Columbia and 4 others

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