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Clareo Health | Lung Cancer Clinical Trials in Philadelphia | 481 Studies

Clinical Trials Lung CancerPhiladelphia

Lung Cancer Clinical Trials in Philadelphia

Find 481 clinical trials for lung cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Philadelphia

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 221-240 of 481 trials

Active not recruitingComparing Photon Therapy To Proton Therapy To Treat Patients With Lung CancerThis randomized phase III trial studies proton chemoradiotherapy to see how well it works compared to photon chemoradiotherapy in treating patients with stage II-IIIB non-small…NCT01993810·Jacksonville, Florida and 29 others

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Data from ClinicalTrials.govTerms

CompletedSafety Study of Cetuximab in Combination With Cisplatin and Vinorelbine to Treat Advanced Non-small Cell Lung CancerThe purpose of the study is to determine if U.S. manufactured Cetuximab can be safely used for the treatment of Non-Small Cell Lung Cancer in combination with Cisplatin and…NCT01109524·Casa Grande, Arizona and 21 others

TerminatedBempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid TumorsThis study is to assess the safety and tolerability, and to assess the preliminary clinical benefit of NKTR-214 when combined with pembrolizumab (KEYTRUDA®) with or without…NCT03138889·Fayetteville, Arkansas and 37 others

Active not recruitingA Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung CancerThis is a Phase III, randomised, double-blind, multicentre, international study assessing the efficacy and safety of durvalumab (MEDI4736) in combination with oleclumab (MEDI9447)…NCT05221840·San Diego, California and 201 others

CompletedStudy Comparing Veliparib Plus Carboplatin and Paclitaxel Versus Investigator's Choice of Standard Chemotherapy in Adults Receiving First Cytotoxic Chemotherapy for Metastatic or Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC) and Who Are Current or Former SmokersThe purpose of this study is to evaluate the safety and efficacy of veliparib plus carboplatin and paclitaxel versus the Investigator's choice of standard chemotherapy in adults…NCT02264990·Huntsville, Alabama and 139 others

CompletedStudy of REGN 2810 Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC)The primary objectives of the study are: * To compare the overall survival (OS) of cemiplimab versus standard-of-care platinum-based chemotherapies in the first-line treatment of…NCT03088540·Albury, New South Wales and 191 others

CompletedErlotinib vs. Standard Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) and Eastern Cooperative Oncology Group (ECOG)Performance Status (PS) 2The purpose of this noncomparative study is to obtain preliminary estimates of the efficacy of erlotinib and standard chemotherapy in patients with advanced, previously untreated…NCT00085839·Greenbrae, California and 18 others

CompletedS1403, Afatinib Dimaleate With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage IV or Recurrent, EGFR Mutation Positive Non-small Cell Lung CancerThis randomized phase II/III trial studies how well afatinib dimaleate with cetuximab works and compares it with afatinib dimaleate alone in treating patients with newly diagnosed…NCT02438722·Fort Smith, Arkansas and 637 others

Active not recruitingOsimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior OsimertinibThis study (the SAVANNAH study) will investigate the efficacy of osimertinib in combination with savolitinib in patients with EGFRm+ and MET+, locally advanced or metastatic NSCLC…NCT03778229·La Jolla, California and 89 others

TerminatedS0819: Carboplatin and Paclitaxel With or Without Bevacizumab and/or Cetuximab in Treating Patients With Stage IV or Recurrent Non-Small Cell Lung CancerThis randomized phase III trial studies carboplatin and paclitaxel to compare how well they work with or without bevacizumab and/or cetuximab in treating patients with stage IV or…NCT00946712·Anniston, Alabama and 797 others

TerminatedGenetic Predictors of Benefit to PembrolizumabThe primary objective is to determine if mutation load underlies sensitivity to pembrolizumab alone and in combination with chemotherapy.NCT02710396·New York, New York and 1 other

TerminatedStudy to Assess Safety and Tolerability of MLN8237, In Combination With Erlotinib to Treat Non-Small Cell Lung CancerThis phase I/II trial studies the side effects and the best dose of MLN8237 when given together with erlotinib hydrochloride and to see how well it works in treating patients with…NCT01471964·Philadelphia, Pennsylvania

Active not recruitingComparison of Different Types of Surgery in Treating Patients With Stage IA Non-Small Cell Lung CancerRATIONALE: Wedge resection or segmentectomy may be less invasive types of surgery than lobectomy for non-small cell lung cancer and may have fewer side effects and improve…NCT00499330·Birmingham, Alabama and 385 others

CompletedTPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced CancersThis is a phase 1/1b open label, multicenter dose escalation and dose expansion study to investigate the safety, tolerability and anti-tumor activity of TPST-1120, a small…NCT03829436·San Francisco, California and 10 others

CompletedPhase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic TumorsThis is a two-agent, open-label, non-randomized, Phase 1/2 dose escalation and dose expansion study of combinatorial oral vorolanib plus infusional nivolumab in patients with…NCT03583086·Palo Alto, California and 6 others

TerminatedNivolumab Plus Cisplatin/Pemetrexed or Cisplatin/Gemcitabine as Induction in Resectable Non-Small Cell Lung CancerThis phase II trial studies how well Nivolumab, Cisplatin, and Pemetrexed Disodium or Gemcitabine Hydrochloride in treating patients with stage I-IIIA non-small cell lung cancer…NCT03366766·Abington, Pennsylvania and 1 other

CompletedCetuximab in Treating Patients With Recurrent or Stage IIIB or Stage IV Lung CancerRATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00103207·Aurora, Colorado and 156 others

CompletedSunitinib Malate as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Treated With Combination ChemotherapyThis randomized phase III trial studies sunitinib malate to see how well it works when given as maintenance therapy (meaning it is approved for treatment after chemotherapy) in…NCT00693992·Anniston, Alabama and 483 others

Active not recruitingHER3-DXd (Patritumab Deruxtecan; U3-1402) in Combination With Osimertinib in Subjects With Locally Advanced or Metastatic EGFR-mutated Non-Small Cell Lung CancerThis study includes a Dose Escalation Part to identify the recommended combination dose (RCD) and a Dose Expansion Part to further evaluate efficacy and safety.NCT04676477·Santa Monica, California and 30 others

Active not recruitingA Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced MalignanciesThe primary purpose of this study is to assess the safety and tolerability of AB801 in participants with advanced malignancies, and to determine a recommended AB801 dose for…NCT06120075·Denver, Colorado and 9 others

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