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Clareo Health | Lung Cancer Clinical Trials in Ohio | 865 Studies

Clinical Trials Lung CancerOhio

Lung Cancer Clinical Trials in Ohio

Find 865 clinical trials for lung cancer near Ohio. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Ohio

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 865 trials

CompletedBevacizumab, Paclitaxel, and Carboplatin Before Surgery in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-Small Cell Lung CancerRATIONALE: Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread.NCT00025389·Chicago, Illinois and 1 other TerminatedAdagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)This study will evaluate the safety, MTD and/or RP2D, PK, and clinical activity of the combination of adagrasib with nab-sirolimus in patients with advanced solid tumors/NSCLC…NCT05840510·Cleveland, Ohio and 2 others CompletedA Study of Combination Therapies With Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung CancerThis study will test whether vaccination with viagenpumatucel-L combined with strategies to modulate the immune response is safe for patients with non-small cell lung…NCT02439450·Tucson, Arizona and 15 others

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Data from ClinicalTrials.govTerms

CompletedA Study of Relatlimab Plus Nivolumab in Combination With Chemotherapy vs. Nivolumab in Combination With Chemotherapy as First Line Treatment for Participants With Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)The purpose of this study is to assess the safety profile of relatlimab plus nivolumab in combination with platinum doublet chemotherapy (PDCT) and to determine if nivolumab plus…NCT04623775·Duarte, California and 124 others

Active not recruitingPhase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)This is a Phase 1b/2 study evaluating the anti-PD1 antibody, cemiplimab, in combination with either S095018 (anti-TIM3 antibody), S095024 (anti-CD73 antibody), or S095029…NCT06162572·Detroit, Michigan and 55 others

Active not recruitingA Pilot Study of Blood-based Biomarkers for Response to Immune Checkpoint InhibitorsA pilot study evaluating baseline and on-treatment changes in tumor fraction (TFx) in peripheral blood in patients with NSCLC and RCC being treated with checkpoint inhibitor…NCT06630429·Columbus, Ohio

Active not recruitingTesting the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung CancerThis phase II trial compares cabozantinib alone and the combination of cabozantinib and nivolumab to standard chemotherapy in the treatment of patients with non-squamous non-small…NCT04310007·Birmingham, Alabama and 610 others

TerminatedA Phase 1 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK PathwayThis is a Phase 1, open-label, multicenter, study evaluating the safety, tolerability, PK, PD, and anti-tumor activity of MRTX0902 alone and in combination with MRTX849…NCT05578092·New Haven, Connecticut and 17 others

Approved for marketingExpanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) ActivationExpanded access for participants with cancer with RET activation who are ineligible for an ongoing selpercatinib (also known as LOXO-292) clinical trial or have other…NCT03906331·Goodyear, Arizona and 63 others

TerminatedA Phase 1b Trial of ATRC-101 in Adults With Advanced Solid MalignanciesATRC-101-A01 is a Phase 1b, open-label dose escalation and expansion trial of ATRC-101, an engineered fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a…NCT04244552·Phoenix, Arizona and 18 others

RecruitingPhase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic AlterationsThe purpose of this study is to evaluate efficacy and safety of Dato-DXd in combination with rilvegostomig or rilvegostomig monotherapy compared with pembrolizumab monotherapy as…NCT06357533·Anchorage, Alaska and 288 others

TerminatedStudy to Evaluate Safety, Pharmacokinetics, and Efficacy of Rociletinib (CO-1686) in Previously Treated Mutant Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Cancer (NSCLC) PatientsRociletinib is a novel, potent, small molecule irreversible tyrosine kinase inhibitor (TKI) that selectively targets mutant forms of the epidermal growth factor receptor (EGFR)…NCT01526928·Duarte, California and 48 others

CompletedSafety and Efficacy Study of Abraxane as Maintenance Treatment After Abraxane Plus Carboplatin in 1st Line Stage IIIB / IV Squamous Cell Non-small Cell Lung CancerMaintenance treatment of advanced stage squamous cell NSCLC.NCT02027428·Huntsville, Alabama and 118 others

TerminatedRadiation Therapy or Observation After Chemotherapy in Treating Patients With Stage IV Non-Small Cell Lung CancerRATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Sometimes, after chemotherapy, the tumor may not need more treatment until it progresses.NCT00776100·Scottsdale, Arizona and 167 others

Active not recruitingStudy of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of durvalumab + tremelimumab combination therapy versus platinum-based…NCT02542293·Anaheim, California and 209 others

CompletedStudy of DF1001 in Patients With Advanced Solid TumorsDF1001-001 is a study of a new molecule that targets natural killer (NK) cells and T-cell activation signals to specific receptors on cancer cells.NCT04143711·Irvine, California and 43 others

CompletedA Phase 1b Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Non-small Cell Lung CancerThe purpose of this study is to determine if MEDI4736 will be adequately tolerated in combination with tremelimumab in subjects with advanced non-small cell lung cancer (NSCLC).NCT02000947·Birmingham, Alabama and 68 others

CompletedStudy of XB002 in Subjects With Solid Tumors (JEWEL-101)This is a Phase 1, open-label, multicenter, dose-escalation and expansion study evaluating the safety, tolerability, PK, pharmacodynamics, and clinical antitumor activity of XB002…NCT04925284·Birmingham, Alabama and 94 others

CompletedIrofulven in Treating Patients With Relapsed or Refractory Non-small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003666·Birmingham, Alabama and 47 others

CompletedErlotinib or Placebo Following Chemoradiotherapy (Chemo/RT) in Stage III Non-Small Cell Lung Cancer (NSCLC)This is a national, randomized, web-based, double-blind study to determine whether erlotinib (Tarceva) compared to placebo improves progression-free survival (PFS) for patients…NCT00153803·Birmingham, Alabama and 64 others

Other Conditions in Ohio

Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma