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Clareo Health | Lung Cancer Clinical Trials in Massachusetts | 759 Studies

Clinical Trials Lung CancerMassachusetts

Lung Cancer Clinical Trials in Massachusetts

Find 759 clinical trials for lung cancer near Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 421-440 of 759 trials

CompletedA Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid TumorsIn this four-part study, NKTR-214 was administered in combination with nivolumab and with/without other anticancer therapies.NCT02983045·La Jolla, California and 57 others

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Data from ClinicalTrials.govTerms

RecruitingTesting Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 ChangeThis phase II trial studies how well osimertinib works in treating patients with non-small cell lung cancer with EGFR exon 20 insertion mutation that is stage IIIB-IV or has come…NCT03191149·Anchorage, Alaska and 346 others

Active not recruitingA Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)This is a Phase I/II, open-label, multi-center, multi-national, dose escalation, single agent study to assess the safety, tolerability, PK, PD, immunogenicity and anti-tumor…NCT02912949·Phoenix, Arizona and 63 others

RecruitingTesting the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])This phase III ALCHEMIST treatment trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer…NCT04267848·Anchorage, Alaska and 1150 others

CompletedA Study of Alectinib (CH5424802/RO5424802) in Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer (NSCLC)This non-randomized, open-label, multicenter study will evaluate the safety and efficacy of alectinib in participants with ALK-rearranged non-small cell lung cancer who failed…NCT01871805·Birmingham, Alabama and 41 others

Active not recruitingEmulation of the CheckMate 017/057 (NCT01642004 and NCT01673867) Trials Using Specialty Oncology Electronic Health Records DatabasesInvestigators are building an empirical evidence base for real-world data through large-scale emulation of randomized controlled trials.NCT07485166·Somerville, Massachusetts

CompletedS9925: Collecting and Storing Samples From Patients With Lung CancerRATIONALE: Collecting and storing samples of tissue, blood, and sputum from patients with cancer to study in the laboratory may help the study of cancer in the future.NCT00920010·Mobile, Alabama and 430 others

TerminatedProton Radiation Therapy With Cisplatin and Etoposide Followed by Surgery in Stage III Non-Small Cell Lung CancerThis research study is looking at an alternative way of delivering radiation therapy with protons.NCT01565772·Boston, Massachusetts

CompletedA Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent MalignanciesThe purpose of this study is to determine the safety and effectiveness of MDX-1106 in patients with certain types of cancer.NCT00730639·Scottsdale, Arizona and 12 others

TerminatedCediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung CancerThis phase I trial is studying the side effects and best dose of cediranib maleate when given together with whole brain radiation therapy in treating patients with brain…NCT00937482·Boston, Massachusetts

CompletedErlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung CancerThis randomized phase II trial studies how well erlotinib hydrochloride with or without carboplatin and paclitaxel works in treating patients with stage III-IV non-small cell lung…NCT00126581·Castro Valley, California and 95 others

SuspendedJSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway MutationsThis is a Phase 1 study of JSI-1187 as monotherapy and in combination with dabrafenib for the treatment of advanced solid tumors with MAPK pathway mutations, including mutations…NCT04418167·Phoenix, Arizona and 6 others

CompletedA Study of TAK-788 in Adults With Non-Small Cell Lung CancerThis study is about a medicine called TAK-788, also known as mobocertinib, given to adults with non-small cell lung cancer.NCT02716116·Birmingham, Alabama and 61 others

TerminatedA Study of EGF816 and Gefitinib in TKI-naïve EGFR-mutant Non-Small Cell Lung CancerThis research study is studying a combination of drugs as a possible treatment for EGFR mutation-positive lung cancer. The drugs involved in this study are: * EGF816 * GefitinibNCT03292133·Boston, Massachusetts

No longer availableAZD9291 US Expanded Access ProgramTo provide access to AZD9291 for adult patients with advanced/metastatic, epidermal growth factor receptor T790M mutation-positive non-small cell lung cancer.NCT02451852·Anaheim, California and 31 others

CompletedA Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced CancersThe purpose of this study was to evaluate the safety and tolerability of escalating doses of the MM-121 plus cetuximab and the MM-121 plus cetuximab plus irinotecan combination.NCT01451632·San Francisco, California and 3 others

CompletedEarly Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family CaregiversThe study intervention consists of the early integration of palliative care services into standard oncology care in an outpatient setting for patients with advanced lung and…NCT02349412·La Jolla, California and 22 others

CompletedA Study of Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Advanced NSCLC* To evaluate the safety and tolerability of escalating doses of ERAS-007 or ERAS-601 in combination with other cancer therapies in study participants with advanced non-small cell…NCT04959981·Duarte, California and 10 others

WithdrawnCombination Chemotherapy in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy such as gemcitabine, carboplatin, and paclitaxel use different ways to stop tumor cells from dividing so they stop growing or die.NCT00054392·Loma Linda, California and 56 others

RecruitingThis is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.The purpose of the study is to compare how the new combination treatment (Sigvotatug Vedotin plus pembrolizumab) works compared to pembrolizumab alone in patients with non-small…NCT06758401·Fullerton, California and 388 others

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