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Clareo Health | Lung Cancer Clinical Trials in Massachusetts | 755 Studies

Clinical Trials Lung CancerMassachusetts

Lung Cancer Clinical Trials in Massachusetts

Find 755 clinical trials for lung cancer near Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 401-420 of 755 trials

Active not recruitingPlatform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C MutationThis is Phase Ib/II, multicenter, open-label adaptive platform study of JDQ443 with select therapies in patients with advanced solid tumors harboring the KRAS G12C mutation.NCT05358249·Boston, Massachusetts and 12 others TerminatedPhase IIB/III Of TG4010 Immunotherapy In Patients With Stage IV Non-Small Cell Lung CancerThis is a Phase IIb/III randomized, double-blind, placebo-controlled study to compare the efficacy and safety of first-line therapy combined with TG4010 or placebo in stage IV…NCT01383148·Scottsdale, Arizona and 71 others

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Data from ClinicalTrials.govTerms

CompletedA Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLCThis research study is studying a type of radiation therapy called Stereotactic Body Radiation Therapy (SBRT) as a possible treatment for stage IV non-small cell lung cancer…NCT02314364·Boston, Massachusetts

CompletedLUX Lung 2 Phase II Single Arm BIBW 2992 "Afatinib" in NSCLC With EGFR Activating MutationsThe primary objective of this open-label, single arm Phase II trial is to explore the efficacy of BIBW 2992 defined by the objective response rate (CR, PR) as determined by RECIST…NCT00525148·Bakersfield, California and 29 others

TerminatedA Study of Zilovertamab Vedotin (MK-2140/VLS-101) in Participants With Solid Tumors (MK-2140-002)This is a study evaluating the efficacy, safety, and pharmacokinetics of zilovertamab vedotin in participants with metastatic solid tumors including previously treated cancers of…NCT04504916·Hollywood, Florida and 13 others

CompletedPhase III Study of the Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC)The purpose of this study is to determine if the investigational drug GTx-024 can help subjects with non-small cell lung cancer increase physical function and maintain or gain…NCT01355484·Birmingham, Alabama and 26 others

CompletedA Personal Cancer Vaccine (NEO-PV-01) With Pembrolizumab and Chemotherapy for Patients With Lung CancerThe purpose of this study is to find out if treatment with NEO-PV-01 in combination with pembrolizumab and chemotherapy (pembrolizumab/chemotherapy) is safe and useful for…NCT03380871·Santa Monica, California and 4 others

CompletedNivolumab in Combination With Chemotherapy, or Nivolumab in Combination With Ipilimumab, in Advanced EGFR-Mutant or ALK-Rearranged NSCLCThis research study is studying a drug intervention as a possible treatment for lung cancer.NCT03256136·Boston, Massachusetts and 2 others

CompletedVinorelbine + Cisplatin or No Further Therapy in Non-small Cell Lung Cancer That Has Been Surgically RemovedRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00002583·Birmingham, Alabama and 154 others

RecruitingA Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid TumorsThe purpose of this study is to find out whether the study drug, LY4052031, is safe, tolerable and effective in participants with advanced, or metastatic solid tumors including…NCT06465069·Duarte, California and 38 others

CompletedPemetrexed Disodium, Carboplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Stage III Non-Small Cell Lung CancerRATIONALE: Pemetrexed disodium may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00117962·Arroyo Grande, California and 70 others

CompletedStudy of Gemcitabine/Platinum +/- Cetuximab as First-Line Treatment for Patients With Advanced/Metastatic Non-Small Cell Lung CancerThe primary purpose of this study is to estimate the number of patients with non-small cell lung cancer whose tumor responds to the treatments given in this study.NCT00112346·Mobile, Alabama and 37 others

CompletedDose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With PembrolizumabThis clinical trial is a Phase 1/2, open-label, sequential-group, dose-escalation and cohort expansion study to determine the safety and preliminary anti-tumor activity of FLX475…NCT03674567·Gilbert, Arizona and 34 others

RecruitingPhase 1 Study of OP-3136 in Advanced or Metastatic Solid TumorsThis is a first-in-human, open-label, multicenter phase 1 study to evaluate safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of…NCT06784193·Sarasota, Florida and 7 others

RecruitingA Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid TumorsThe purpose of the study is to explore the safety and effects of the study drug (PF-08046876) in people diagnosed with advanced cancer of the bladder, lung, head and neck…NCT07090499·Duarte, California and 30 others

CompletedAdagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2)This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 in combination with TNO155 in patients with advanced solid…NCT04330664·Los Angeles, California and 16 others

Active not recruitingA Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 MutationsDESTINY-Lung04 will investigate the efficacy and safety of Trastuzumab Deruxtecan (T-DXd) versus Standard of Care (SoC) as first-line treatment of Non-Small Cell Lung Cancer…NCT05048797·Anchorage, Alaska and 129 others

CompletedStudy of Safety and Efficacy of LEE011 and Ceritinib in Patients With ALK-positive Non-small Cell Lung Cancer.This was a Phase Ib/II study of the ALK inhibitor ceritinib in combination with the CDK4/6 inhibitor LEE011 in patients with ALK-positive non-small cell lung cancer.NCT02292550·Boston, Massachusetts and 7 others

CompletedProton Radiotherapy for Patients With Non-Small Cell Lung Cancer (NSCLC)The goal of this clinical research study is to learn if escalated/accelerated proton radiotherapy can improve the control of Non-Small Cell Lung Cancer (NSCLC) and decrease side…NCT00495040·Boston, Massachusetts and 1 other

TerminatedStudy of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or MutationsA phase 1/2, first-in-human, open-label study to determine the safety, tolerability, PK, and preliminary efficacy of the novel RET/SRC inhibitor TPX-0046 in adult subjects with…NCT04161391·La Jolla, California and 20 others

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