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Clareo Health | Lung Cancer Clinical Trials in Boston | 649 Studies

Clinical Trials Lung CancerBoston

Lung Cancer Clinical Trials in Boston

Find 649 clinical trials for lung cancer near Boston, Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Boston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 649 trials

TerminatedStudy to Evaluate Safety, Pharmacokinetics, and Efficacy of Rociletinib (CO-1686) in Previously Treated Mutant Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Cancer (NSCLC) PatientsRociletinib is a novel, potent, small molecule irreversible tyrosine kinase inhibitor (TKI) that selectively targets mutant forms of the epidermal growth factor receptor (EGFR)…NCT01526928·Duarte, California and 48 others

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Data from ClinicalTrials.govTerms

CompletedA Study Of PF-06463922 An ALK/ROS1 Inhibitor In Patients With Advanced Non Small Cell Lung Cancer With Specific Molecular AlterationsPhase 1 and 2 trial to study the safety, pharmacokinetics, pharmacodynamics, patient reported outcomes and efficacy of PF-06463922 in ALK + advanced non-small cell lung cancer…NCT01970865·Fayetteville, Arkansas and 76 others

CompletedA Phase 1b Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Non-small Cell Lung CancerThe purpose of this study is to determine if MEDI4736 will be adequately tolerated in combination with tremelimumab in subjects with advanced non-small cell lung cancer (NSCLC).NCT02000947·Birmingham, Alabama and 68 others

TerminatedA Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid TumorsThis study is about TAK-500, given either alone or with pembrolizumab, in adults with select locally advanced or metastatic solid tumors.NCT05070247·Birmingham, Alabama and 11 others

Active not recruitingStudy of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid TumorsCancer is a condition where cells in a specific part of body grow and reproduce uncontrollably.NCT04721015·Boston, Massachusetts and 32 others

CompletedA Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy…NCT03849469·Encinitas, California and 27 others

TerminatedA Study of TPX-0131, a Novel Oral ALK Tyrosine Kinase Inhibitor, in Patients With ALK+ Advanced or Metastatic NSCLCA phase 1, first-in-human, open-label study to evaluate the safety, tolerability, PK, and efficacy of the novel ALK inhibitor TPX-0131 in pretreated subjects with ALK+ advanced or…NCT04849273·Orange, California and 14 others

CompletedA Study of DF6002 Alone and in Combination With NivolumabThe purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and in combination with Nivolumab…NCT04423029·Orange, California and 31 others

RecruitingLung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung CancerThis screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and…NCT03851445·Birmingham, Alabama and 1228 others

CompletedA Double-blind Study Evaluating IPI-504 and Docetaxel in Patients With Non-Small Cell Lung CancerThe purpose of this study is to compare the impact of IPI-504 in combination with docetaxel to placebo in combination with docetaxel on life expectancy in patients with Non Small…NCT01362400·Chandler, Arizona and 64 others

Active not recruitingStudy of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C MutationThis is a phase Ib/II open label study.NCT04699188·Atlanta, Georgia and 37 others

CompletedPhase II Study in Patients With Recurrent Non-Small-Cell Lung CancerDetermine tumor response rate and time to disease progression, survival and safety in total populations.NCT00063388·Aventura, Florida and 7 others

UnknownFludeoxyglucose F18 Positron Emission Tomography Imaging In Assessing Patients Before and After Treatment for Locally Advanced Non-Small Cell Lung CancerRATIONALE: Imaging procedures, such as fludeoxyglucose F18 positron emission tomography (\^18FDG-PET), may improve the ability to detect disease progression and help doctors…NCT00083083·Birmingham, Alabama and 48 others

Active not recruitingA Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid TumorsThe purpose of this study is to find out whether the study drug, LY4101174, is safe, tolerable and effective in participants with select advanced or metastatic solid tumors.NCT06238479·Orlando, Florida and 27 others

RecruitingA Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung CancerThe purpose of this study is to evaluate the efficacy and safety of divarasib and pembrolizumab compared with pembrolizumab and pemetrexed and carboplatin or cisplatin, for the…NCT06793215·Anchorage, Alaska and 298 others

RecruitingAPL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid TumorsTo assess: * efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET…NCT03175224·Los Angeles, California and 34 others

TerminatedDS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing or -Mutated Non-Small Cell Lung CancerThe primary objective of this trial is to evaluate the efficacy of trastuzumab deruxtecan in HER2-overexpressing and/or HER2-mutated advanced NSCLC participants.NCT03505710·La Jolla, California and 20 others

TerminatedVeliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Biliary, Pancreatic, Urothelial, or Non-Small Cell Lung CancerThis phase I clinical trial is studying the side effects and best dose of veliparib and gemcitabine hydrochloride when given with cisplatin in treating patients with advanced…NCT01282333·Boston, Massachusetts and 2 others

TerminatedStudy of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced MalignanciesThis is a Phase 1, open-label, first-in-human study of CTX-471 administered as a monotherapy or in combination with pembrolizumab in patients with metastatic or locally advanced…NCT03881488·Ocala, Florida and 9 others

CompletedCAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumorsNCT03504488·Tucson, Arizona and 58 others

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