Kidney Disease Clinical Trials

Showing 2261-2280 of 3,902 trials

Nivolumab in Treating Patients With High-Risk Kidney Cancer Before Surgery

NCT02595918

This pilot phase I trial studies the side effects of nivolumab and how well it works in treating patients with high-risk kidney cancer before surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

Clear Cell Renal Cell CarcinomaMetastatic Renal Cell CarcinomaStage I Renal Cell Cancer AJCC v6 and v7+3 more

National Cancer Institute (NCI)19 participantsStarted May 2016

New York, New York, United States

COMPLETEDNA

Effects of Physical Activities on the Expression of Nrf2 and Nf-kb Hemodialysis Patients

NCT02718638

Oxidative stress and inflammation are cardiovascular risk factors in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD). Nuclear transcription factors play roles in the coordinated expression of genes involved in inflammation, such as nuclear factor Kappa B (NFkB) that increase the cytokines synthesis and Nuclear factor erythroid 2-related factor 2 (Nrf2) that increase the transcription of genes encoding enzymes of phase II detoxifying and antioxidant enzymes. The aim of this study was to evaluate the effects of resistance exercise program on the expression of transcription factors Nrf2 and NF-kB in HD patients.

Chronic Kidney DiseaseHypertensionDiabetes

Universidade Federal Fluminense40 participantsStarted Jan 2013

Rio de Janeiro, Rio de Janeiro, Brazil

Nivolumab in Treating Patients With High-Risk Kidney Cancer Before Surgery

Effects of Physical Activities on the Expression of Nrf2 and Nf-kb Hemodialysis Patients

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