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Clareo Health | Heart Disease Clinical Trials in Pennsylvania | 27 Studies

Clinical Trials Heart DiseasePennsylvania

Heart Disease Clinical Trials in Pennsylvania

Find 27 clinical trials for heart disease near Pennsylvania. Connect with research centers in your area.

All Heart Disease trials nationwide All trials in Pennsylvania

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

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Showing 1-20 of 27 trials

Active not recruitingThe TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 DiabetesThis research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce…NCT01047735·Pittsburgh, Pennsylvania Active not recruitingPROACTIVE-HF IDE Trial Heart Failure NYHA Class IIIThis is a prospective, open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart…NCT04089059·Birmingham, Alabama and 73 others

Heart Disease Trials in Other Cities

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Data from ClinicalTrials.govTerms

CompletedRandomized Endo-Vein Graft ProspectiveCoronary artery bypass grafting (CABG) is the most common major surgical procedure in the United States with over 300,000 cases performed each year.NCT01850082·Tucson, Arizona and 15 others

CompletedVasodilator Therapy for Heart Failure and Preserved Ejection FractionThe main objective is to test the effect of prolonged therapy (24 weeks) with isosorbide dinitrate ± hydralazine on arterial wave reflections (primary endpoint).NCT01516346·Philadelphia, Pennsylvania

RecruitingA Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart DiseaseThe goal of this clinical study is to evaluate the safety and efficacy of percutaneous pulmonary artery denervation with the Multi-Pole Pulmonary Artery Radiofrequency Ablation…NCT07214376·Tucson, Arizona and 15 others

WithdrawnGamification to Increase Mobility in the HospitalLow mobility is a mediator for poor outcomes of hospital care.NCT04300764·Philadelphia, Pennsylvania

CompletedStudy to Investigate CSL112 in Subjects With Acute Coronary SyndromeThis is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major…NCT03473223·Alexander City, Alabama and 902 others

CompletedPrevention of Serious Adverse Events Following AngiographyThe purpose of this research study is to compare the effectiveness of intravenous isotonic sodium bicarbonate with intravenous isotonic sodium chloride and oral N-acetylcysteine…NCT01467466·Tucson, Arizona and 53 others

RecruitingPharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults…NCT04278404·Phoenix, Arizona and 51 others

CompletedImproving Quality by Maintaining Accurate Problems in the EHRThe overall goal of the IQ-MAPLE project is to improve the quality of care provided to patients with several heart, lung and blood conditions by facilitating more accurate and…NCT02596087·Boston, Massachusetts and 3 others

CompletedPrevention of Autogenous Vein Graft Failure in Coronary Artery Bypass ProceduresThe purpose of this study is to determine the efficacy of graft pretreatment with CGT003 (E2F Duplex Decoy), as compared to placebo, on the incidence of patients experiencing vein…NCT00042081·Birmingham, Alabama and 153 others

WithdrawnStudy Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise CapacityThe purpose of the present prospective, randomized study is to investigate the clinical effectiveness of standardized left ventricular reconstruction surgery (LVR).NCT00326690·Los Angeles, California and 9 others

RecruitingPROACTIVE-HF-2 Trial Heart Failure NYHA Class II and IIIThis is a prospective, multi-center, open label, randomized control clinical trial evaluating the safety and efficacy of the Cordella™ Pulmonary Artery Sensor System in NYHA Class…NCT05934487·Phoenix, Arizona and 47 others

CompletedEffect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD)The primary objective is to assess the effect of 2 dose levels of SNF472 (300 mg and 600 mg) compared to placebo on the progression of coronary artery calcium volume score over a…NCT02966028·Bakersfield, California and 74 others

RecruitingRemote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) TrialThis is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated…NCT04982419·Pittsburgh, Pennsylvania and 2 others

RecruitingTrial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureThe purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of…NCT06526195·Phoenix, Arizona and 67 others

CompletedA Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart FailureThe purpose of this study is to assess the effectiveness and safety of rivaroxaban compared with placebo (inactive medication), in reducing the risk of death, myocardial…NCT01877915·Alexander City, Alabama and 561 others

CompletedReal World Expanded Multicenter Study of the MitraClip® System (REALISM)Prospective, multicenter, continued access registry of the MitraClip® Cardiovascular Valve Repair System in the treatment of mitral valve regurgitation.NCT01931956·Los Angeles, California and 37 others

RecruitingCombined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)This is a two-part, phase 2b and phase 3 combined prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study.NCT05485961·Decatur, Alabama and 565 others

Active not recruitingThe Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney…NCT06383390·Alabaster, Alabama and 741 others

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