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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 457 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 457 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 457 trials

RecruitingA Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid TumorsThis is a two-part Phase 1, open label, multi-center, single arm, non-randomized, multiple dose, safety, pharmacokinetic (PK) and preliminary efficacy study of single agent…NCT06326411·San Francisco, California and 22 others CompletedPembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid TumorsThis is an open-label, multicenter, Phase 1b platform study in subjects with advanced or metastatic solid tumors (Part 1a) and subjects with selected solid tumors (Part 1b and…NCT02646748·San Francisco, California and 16 others

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Data from ClinicalTrials.govTerms

RecruitingA Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid TumorsKB707-01 is a Phase 1/2, open-label, multicenter, dose escalation and expansion study.NCT05970497·Los Angeles, California and 14 others

RecruitingTebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator…NCT05549297·Phoenix, Arizona and 81 others

CompletedSafety Study of Adenovirus Vector Engineered to Express hIL-12 in Combination With Activator Ligand to Treat MelanomaThis research study involves two investigational drugs, an Activator Ligand (INXN-1001) in combination with an Adenovirus Vector Engineered to Express hIL-12 (INXN-2001).NCT01397708·Los Angeles, California and 8 others

CompletedA Clinical Trial of KVA12123 [TBS-2025] Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)The goal of this clinical trial is to test the safety and efficacy of KVA12123 alone or combined with pembrolizumab in patients with advanced solid tumors.NCT05708950·Santa Monica, California and 6 others

CompletedA Study of RO5185426 in Patients With Metastatic MelanomaThis is an open-label, non-comparative, multicenter, expanded access study of RO5185426 in patients who have received prior systemic therapy for metastatic melanoma and who have…NCT01248936·Tucson, Arizona and 27 others

RecruitingPan-tumor MRD StudyThe purpose of this observational study is to collect clinical information, blood, and tumor tissue samples from participants diagnosed with stage I, stage II, or operable stage…NCT06605404·Birmingham, Alabama and 46 others

TerminatedNY-ESO-1 Vaccine in Combination With Ipilimumab in Patients With Unresectable or Metastatic MelanomaThis was a Phase 1, open-label, non-randomized study of the combination of NY-ESO-1 plus ipilimumab in patients with unresectable or metastatic melanoma for whom treatment with…NCT01810016·New York, New York and 4 others

Active not recruitingStudy of ARRY-614 Plus Either Nivolumab or Nivolumab+IpilimumabIn this study, the Phase Ib portion aims to establish safety and tolerability of ARRY-614 with either nivolumab or ipilimumab and to determine a recommended phase II dose of…NCT04074967·Pittsburgh, Pennsylvania

SuspendedPropranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by SurgeryThis phase Ib/II trial studies the side effects and best dose of propranolol hydrochloride when given together with pembrolizumab and how well they work in treating patients with…NCT03384836·Atlanta, Georgia and 3 others

CompletedRandomised Study to Compare the Efficacy of AZD6244 vs TMZThe primary purpose of this study is to compare the efficacy of AZD6244 (ARRY-142886) with temozolomide in patients with advanced melanomaNCT00338130·Santa Monica, California and 32 others

TerminatedA Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their TumorThe purpose of this clinical trial is to evaluate the benefit of the immunotherapeutic product GSK 2132231A in preventing disease relapse when given to melanoma patients, after…NCT00796445·Birmingham, Alabama and 256 others

CompletedDERM US and EU Validation StudyThis study aims establish the effectiveness of Image Analysing Algorithm (DERM) to identify melanoma, Squamous Cell Carcinoma (SCC) and Basal Cell Carcinoma (BCC) when used to…NCT05126173·Redwood City, California and 15 others

CompletedVorinostat in Treating Patients With Metastatic or Unresectable MelanomaThis phase II trial is studying how well vorinostat works in treating patients with metastatic or unresectable melanoma.NCT00121225·Philadelphia, Pennsylvania and 4 others

CompletedA Study of GSK2118436 in BRAF Mutant Metastatic Melanoma to the BrainThis study is designed to assess the efficacy, pharmacokinetics, safety, and tolerability of an oral, twice daily dose of 150 mg GSK2118436 administered to subjects with BRAF…NCT01266967·Los Angeles, California and 23 others

RecruitingA Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant TumorsThis study will evaluate the safety, efficacy, optimal dose, and pharmacokinetics (PK) of BNT326 as monotherapy (Part 1) and as combination treatment with immunotherapeutic agents…NCT07070232·Phoenix, Arizona and 75 others

CompletedA Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic CancersThis is a study of CDX-1127, a therapy that targets the immune system and may act to promote anti-cancer effects.NCT01460134·Scottsdale, Arizona and 9 others

RecruitingImmunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin CancerThis phase II trial tests the combination of nivolumab and ipilimumab with sirolimus and prednisone for the treatment of skin (cutaneous) cancer that cannot be removed by surgery…NCT05896839·La Jolla, California and 25 others

TerminatedKZR-261 in Subjects With Advanced Solid MalignanciesA first-in-human, open-label, multicenter, Phase 1 study of KZR-261 designed to assess the safety and tolerability, preliminary anti-tumor activity, and pharmacokinetics (PK) of…NCT05047536·Los Angeles, California and 11 others

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