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Clareo Health | Heart Disease Clinical Trials in Ohio | 28 Studies

Clinical Trials Heart DiseaseOhio

Heart Disease Clinical Trials in Ohio

Find 28 clinical trials for heart disease near Ohio. Connect with research centers in your area.

All Heart Disease trials nationwide All trials in Ohio

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

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Showing 1-20 of 28 trials

UnknownMYOHEART™ (Myogenesis Heart Efficiency and Regeneration Trial)The MyoCell™ implantation using the MyoCath™ delivery catheter system may have the potential to add a new dimension to the management of post-infarct deterioration of cardiac…NCT00054678·Sunrise, Florida and 4 others CompletedInvestigation to Optimize Hemodynamic Management of Left Ventricular Assist Devices Using the CardioMEMS™This observational post market study is intended to characterize hemodynamic-guided management of patients with an existing left ventricular assist device (LVAD) to protocol…NCT03247829·La Jolla, California and 22 others

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Data from ClinicalTrials.govTerms

TerminatedStudy of the Efficacy and Safety of Tezosentan in Patients With Pre-operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart SurgeryEndothelin-1 is a powerful substance that may be involved in causing hemodynamic instability (problems related to unstable blood pressure) during and after open heart surgery.NCT00458276·Stanford, California and 32 others

CompletedEffect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD)The primary objective is to assess the effect of 2 dose levels of SNF472 (300 mg and 600 mg) compared to placebo on the progression of coronary artery calcium volume score over a…NCT02966028·Bakersfield, California and 74 others

RecruitingTrial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureThe purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of…NCT06526195·Phoenix, Arizona and 67 others

CompletedEvaluation of the Effects of Carperitide in Patients With Congestive Heart FailureThe study will evaluate the safety and efficacy of intravenous infusion of carperitide using pressure measurements inside the heart and great vessels and measuring carperitide…NCT00259038·Huntsville, Alabama and 33 others

CompletedPharmacokinetics of Understudied Drugs Administered to Children Per Standard of CareUnderstudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug…NCT01431326·Anchorage, Alaska and 51 others

CompletedSafety & Efficacy of Adipose-Derived Regenerative Cells in the Treatment of Chronic Myocardial Ischemia (ATHENA II)This is a prospective, randomized, placebo-controlled, double blind safety and efficacy clinical trial.NCT02052427·Cleveland, Ohio

CompletedStudy to Investigate CSL112 in Subjects With Acute Coronary SyndromeThis is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major…NCT03473223·Alexander City, Alabama and 902 others

CompletedRandomized Endo-Vein Graft ProspectiveCoronary artery bypass grafting (CABG) is the most common major surgical procedure in the United States with over 300,000 cases performed each year.NCT01850082·Tucson, Arizona and 15 others

CompletedA Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart FailureThe purpose of this study is to assess the effectiveness and safety of rivaroxaban compared with placebo (inactive medication), in reducing the risk of death, myocardial…NCT01877915·Alexander City, Alabama and 561 others

CompletedPrevention of Autogenous Vein Graft Failure in Coronary Artery Bypass ProceduresThe purpose of this study is to determine the efficacy of graft pretreatment with CGT003 (E2F Duplex Decoy), as compared to placebo, on the incidence of patients experiencing vein…NCT00042081·Birmingham, Alabama and 153 others

RecruitingThe Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH3C) trial is a prospective, unblinded, international multi-center randomized trial of 754 subjects enrolled…NCT05427370·Los Angeles, California and 42 others

CompletedPAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol)Pulmonary arterial hypertension (PAH) is a progressive disease of the pulmonary vasculature leading to elevated pulmonary pressure and right ventricular (RV) dysfunction with…NCT01586156·Cleveland, Ohio

CompletedPrevention of Serious Adverse Events Following AngiographyThe purpose of this research study is to compare the effectiveness of intravenous isotonic sodium bicarbonate with intravenous isotonic sodium chloride and oral N-acetylcysteine…NCT01467466·Tucson, Arizona and 53 others

RecruitingA Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart DiseaseThe goal of this clinical study is to evaluate the safety and efficacy of percutaneous pulmonary artery denervation with the Multi-Pole Pulmonary Artery Radiofrequency Ablation…NCT07214376·Tucson, Arizona and 5 others

RecruitingPharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults…NCT04278404·Phoenix, Arizona and 51 others

RecruitingCombined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)This is a two-part, phase 2b and phase 3 combined prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study.NCT05485961·Decatur, Alabama and 565 others

TerminatedA Phase IIb Study to Investigate the Efficacy and Tolerability of Cinaciguat (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF)A placebo controlled, double-blind and randomized study to assess different doses of a new drug (BAY58-2667) given intravenously, to evaluate if it is safe and can help to improve…NCT01064037·Chicago, Illinois and 69 others

TerminatedIntravascular Ultrasound Derived Virtual Histology and Intracoronary Serum Markers of InflammationPatients enrolled will need treated with an IVUS- VH (intravascular ultrasound-derived virtual histology) which is an arterial stent procedure, that involves threading a tiny wire…NCT00982852·Columbus, Ohio

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