Heart Disease Clinical Trials in Boston

Showing 41-60 of 535 trials

The ENCHANTMENT HIV Study

NCT04153136

Persons with HIV, even those well-treated, are at increased risk for heart disease when compared to the general population. Two hormones called aldosterone and brain natriuretic peptide (BNP), which have been shown to be abnormal in HIV, may be associated with inflammation as well as early changes in structure and function of the heart. This study is being conducted to evaluate whether therapies to block aldosterone and increase BNP levels may reduce the burden and progression of heart failure to improve cardiovascular health.

HIV/AIDSHeart Failure With Preserved Ejection Fraction

Massachusetts General Hospital39 participantsStarted Sep 2020

Boston, Massachusetts, United States

Active Not RecruitingNA< 1 mile

Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

NCT04763200

The purpose of this study is to assess if using the Impella® CP (or Impella® 2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart function and health after a heart procedure compared to the current standard of care.

Left Ventricular DysfunctionCoronary Artery Disease

Abiomed Inc.1,252 participantsStarted Apr 2021

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +96 more locations

The ENCHANTMENT HIV Study

Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

Heart Disease Trials in Other Cities

Lumason® Infusion vs. Bolus Administrations

EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)

Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)

Pediatric Adhesion and New Dermal Approach Study

A Phase IIb Study of AZD5462 in Patients With Chronic Heart Failure

Product Surveillance Registry

COPILOT-HF: Cooperative Program for ImpLementation of Optimal Therapy in Heart Failure

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Conduction System Pacing International Registry (CONSPIRE)

Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry

A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Cardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment

Voice Analysis to Detect Pulmonary Arterial Pressure Changes in Heart Failure

Other Conditions in Boston