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Clareo Health | Heart Disease Clinical Trials in Boston | 28 Studies

Clinical Trials Heart DiseaseBoston

Heart Disease Clinical Trials in Boston

Find 28 clinical trials for heart disease near Boston, Massachusetts. Connect with research centers in your area.

All Heart Disease trials nationwide All trials in Boston

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 1-20 of 28 trials

TerminatedThe Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension StudyThe purpose of this study is to find out if spironolactone added to ambrisentan for Pulmonary Arterial Hypertension (PAH) will increase exercise capacity.NCT02253394·Boston, Massachusetts RecruitingPROACTIVE-HF-2 Trial Heart Failure NYHA Class II and IIIThis is a prospective, multi-center, open label, randomized control clinical trial evaluating the safety and efficacy of the Cordella™ Pulmonary Artery Sensor System in NYHA Class…NCT05934487·Phoenix, Arizona and 47 others

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Data from ClinicalTrials.govTerms

WithdrawnDose Determination Safety and Activity Study of Inhaled NX1011 to Treat Pulmonary Arterial HypertensionThe purpose of this study is to determine the safety and maximum tolerated dose of inhaled NX1011 for the treatment of pulmonary arterial hypertension (PAH).NCT00323024·Phoenix, Arizona and 5 others

RecruitingPharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults…NCT04278404·Phoenix, Arizona and 51 others

Enrolling by invitationEffect of PEEP on Cardiac FunctionThe purpose of this single-center, prospective study is to evaluate the physiologic effect of changes in PEEP on biventricular mechanics and RV-pulmonary arterial (RV-PA) coupling…NCT07531602·Boston, Massachusetts

CompletedNHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR TrialBackground: Replacing a valve in the heart can save many people's lives. The procedure is called transcatheter aortic valve replacement (TAVR).NCT05666713·San Francisco, California and 9 others

CompletedIMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF)Medical imaging is one of the fastest growing sectors in health care and increases in utilization underscore the need to ensure imaging technology is developed and used…NCT01288560·Boston, Massachusetts and 19 others

CompletedRandomized Endo-Vein Graft ProspectiveCoronary artery bypass grafting (CABG) is the most common major surgical procedure in the United States with over 300,000 cases performed each year.NCT01850082·Tucson, Arizona and 15 others

RecruitingCombined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)This is a two-part, phase 2b and phase 3 combined prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study.NCT05485961·Decatur, Alabama and 565 others

RecruitingA Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart DiseaseThe goal of this clinical study is to evaluate the safety and efficacy of percutaneous pulmonary artery denervation with the Multi-Pole Pulmonary Artery Radiofrequency Ablation…NCT07214376·Tucson, Arizona and 18 others

RecruitingANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)The primary objective of this protocol is to develop a comprehensive, multicenter international prospective registry to capture long-term clinical outcomes for adult patients…NCT07559903·Phoenix, Arizona and 18 others

CompletedPrevention of Serious Adverse Events Following AngiographyThe purpose of this research study is to compare the effectiveness of intravenous isotonic sodium bicarbonate with intravenous isotonic sodium chloride and oral N-acetylcysteine…NCT01467466·Tucson, Arizona and 53 others

TerminatedRisk Factors for Coronary Artery Calcification and Left Ventricular Hypertrophy in Hemodialysis PatientsIndividuals with kidney disease are at a higher risk for heart and vascular diseases, including heart attacks and strokes, than those with normal kidney function.NCT01427374·Indianapolis, Indiana and 3 others

Not yet recruitingClinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials StudyThe goal of this prospective, multicenter, non-randomized observational study is to better identify and understand periprocedural myocardial injury among adults undergoing…NCT07848529·Boston, Massachusetts

WithdrawnCalcium, Phosphate, Renal Impairment and Coronary Artery Disease in the Cardio-renal Syndrome, The CAPRICORN-CRS StudyHeart failure (HF) is a major public health problem, which affects about 5 million Americans.HF is when the heart muscle does not pump as much blood as the body needs.NCT00853541·Boston, Massachusetts

CompletedImproving Quality by Maintaining Accurate Problems in the EHRThe overall goal of the IQ-MAPLE project is to improve the quality of care provided to patients with several heart, lung and blood conditions by facilitating more accurate and…NCT02596087·Boston, Massachusetts and 3 others

CompletedStudy to Investigate CSL112 in Subjects With Acute Coronary SyndromeThis is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major…NCT03473223·Alexander City, Alabama and 902 others

CompletedHemodynamic-GUIDEd Management of Heart FailureThe GUIDE-HF IDE clinical trial is intended to demonstrate the effectiveness of the CardioMEMS™ HF System in an expanded patient population including heart failure (HF) patients…NCT03387813·Phoenix, Arizona and 128 others

UnknownStudy of an Intervention to Improve Problem List Accuracy and UseThe aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers…NCT01105923·Boston, Massachusetts

CompletedHeart Muscle Viability and Remodeling in Individuals Post-Heart AttackThe purpose of this study is to assess the effect of heart muscle viability on left ventricular (LV) remodeling after a heart attack; to explore the relationships between retained…NCT00099411·Boston, Massachusetts

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