COVID-19 Clinical Trials in Philadelphia

Showing 61-80 of 203 trials

COVID-19 Close Contact Self-Testing Study

NCT04847479

Widespread testing and contact tracing are critical to controlling the COVID-19 epidemic. Distribution of COVID-19 self-test kits can augment public health contact tracing efforts, as individuals with COVID-19 can distribute self-testing to close contacts. This approach can increase case detection by facilitating testing among exposed individuals, and potentially ameliorate stigma, fear, and medical mistrust associated with COVID-19 among vulnerable populations. The central hypothesis of this study is that distribution of SARS-CoV-2 self-tests to close contacts of among individuals with COVID-19 infection can increase case detection compared with a standard contact referral strategy.

Covid19

University of Pennsylvania3 participantsStarted May 2021

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2/3< 1 mile

Novel Experimental COVID-19 Therapies Affecting Host Response

NCT04924660

The overarching goal of the Master Protocol is to find effective strategies for inpatient management of patients with COVID-19. Therapeutic goals for patients hospitalized for COVID-19 include hastening recovery and preventing progression to critical illness, multiorgan failure, or death. Our objective is to determine whether modulating the host tissue response improves clinical outcomes among patients with COVID-19. The primary analysis will include data from NCT05593770.

COVID-19SARS-CoV-2 InfectionCoronavirus Infection

Sean Collins1,060 participantsStarted Jul 2021

Birmingham, Alabama, United States • Chandler, Arizona, United States • Los Angeles, California, United States +48 more locations

COVID-19 Close Contact Self-Testing Study

Novel Experimental COVID-19 Therapies Affecting Host Response

COVID-19 Trials in Other Cities

PRE-VENT Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer

Assessment of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 Peptide Antigens

Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participants

Covid-19 Infection and Pulmonary Distress Treatment With Zanubrutinib in Hospitalized Participants

Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients

BIO 300 Oral Suspension in Previously Hospitalized Long COVID Patients

IMM-BCP-01 in Mild to Moderate COVID-19

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Predictors of Severe COVID-19 Outcomes

Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.

Evaluation of the RD-X19 Treatment Device in Individuals With Mild COVID-19

Upamostat, a Serine Protease Inhibitor, or Placebo for Treatment of COVID-19 Disease

A Study to Investigate the Prevention of COVID-19 WithVYD222 in Adults with Immune Compromise and in Participants Aged 12 Years or Older Who Are At Risk of Exposure to SARS-CoV-2

Study to Evaluate Safety and Immunogenicity of COVID-19 Vaccine in Children 6 Months to < 12 Years

Study of Monovalent and Bivalent Recombinant Protein Vaccines Against COVID-19 in Adults 18 Years of Age and Older

Study of Mavrilimumab (KPL-301) in Participants Hospitalized With Severe Corona Virus Disease 2019 (COVID-19) Pneumonia and Hyper-inflammation

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19)

A Study to Evaluate the Efficacy, Safety, and Concentration of SNS812 in Mild to Moderate COVID-19 Patients

Other Conditions in Philadelphia