Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Corvus Pharmaceuticals, Inc.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Confirmed positive by polymerase chain reaction (PCR) or antigen test for SARS-CoV-2 with sample collection ≤ 10 days prior to randomization
Covid-19 illness of any duration of symptoms
Hospitalized for Covid-19 for ≤ 5 days with mild to moderate Covid-19 symptoms and meets criteria for either Category 4, Category 5, or Category 6 per 8-point ordinal scale
Adequate organ function
Participants of child-bearing age must agree to use adequate contraception for 6 weeks after study treatment administration
You may not be if
Signs of acute respiratory distress syndrome or respiratory failure necessitating mechanical ventilation at time of screening/randomization or anticipated need for mechanical ventilation
History of severe chronic respiratory disease and requirement for long-term oxygen therapy
Uncontrolled active systemic infection or hemodynamic instability requiring admission to an intensive care unit
Malignant tumor receiving treatment, or other serious systemic diseases affecting life expectancy within 29 days of screening
Receipt of cancer chemotherapy or immunomodulatory drugs during preceding 2 months (steroids for treatment of Covid-19 are acceptable)
Convalescent plasma (CCP) or anti-SARS-CoV-2 monoclonal antibodies administered \<24 hours prior to randomization. Must have recovered from any adverse events related to CCP treatment. Received chloroquine or hydroxychloroquine within last 7 days or during the study
Current participation in other clinical trials including extended access programs
Active deep vein thrombosis or pulmonary embolism within last 6 months
Anticipated discharge from hospital or transfer to another hospital which is not a study site within 48 hours of admission
Active uncontrolled co-morbid disease that may interfere with study conduct or interpretation of findings
Known to be positive for HIV or positive test for chronic HBV infection or positive test for hepatitis C antibody
