COPD Clinical Trials

Showing 1201-1220 of 1,730 trials

Noninvasive Positive Pressure Ventilation in Overlap Syndrome

NCT03184714

Chronic obstructive pulmonary diseases (COPD) coexisting with obstructive sleep apnea is called overlap syndrome (OS). Patients with OS seem to have worse prognosis than patients with only one disorder. Noninvasive positive pressure ventilation is an efficient treatment in obstructive sleep apnea, but the effectiveness in improving outcomes of OS patients is still not fully investigated. The aim of this non-randomized concurrent control trial is to evaluate noninvasive positive pressure ventilation's effectiveness in OS patients.

COPDSleep Apnea SyndromesNon-invasive Positive Pressure Ventilation

Chinese Academy of Medical Sciences, Fuwai Hospital292 participantsStarted Jun 2017

Wuhan, Hubei, China

UNKNOWNNA

Intervention Strategy in Chronic Obstructive Pulmonary Disease With Anxiety and Depression

NCT03187249

Anxiety and depression have negative effect on outcomes of chronic obstructive pulmonary disease (COPD). Intervention strategy including behavioral-cognitive therapy and pulmonary rehabilitation are promising in improving life quality, disease symptom and outcomes. But there's not standard algorithm in China so far. The study aims to compare the effectiveness of these interventions and develop an intervention algorithm of anxiety and depression in COPD.

COPDAnxietyDepression

Chinese Academy of Medical Sciences, Fuwai Hospital500 participantsStarted Jun 2017

Beijing, Beijing Municipality, China

UNKNOWNNA

The Safety and Efficiency of Sildenafil in the Treatment of Severe Post-capillary Pulmonary Hypertension Caused by COPD

NCT03185364

Over half of chronic obstructive pulmonary disease (COPD) patients develop pulmonary hypertension. The current therapy focuses only on the basic disease and there are a lot of controversies about the use of PAH target therapy in group 3 pulmonary hypertension. Our study is to explore whether sildenafil, a pulmonary arterial hypertension (PAH) target drug, could be efficient and safe in improving symptoms and survival of severe pulmonary hypertension caused by COPD.

COPDPulmonary Hypertension

Chinese Academy of Medical Sciences, Fuwai Hospital46 participantsStarted Jun 2017

Wuhan, Hubei, China

Noninvasive Positive Pressure Ventilation in Overlap Syndrome

Intervention Strategy in Chronic Obstructive Pulmonary Disease With Anxiety and Depression

The Safety and Efficiency of Sildenafil in the Treatment of Severe Post-capillary Pulmonary Hypertension Caused by COPD

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