COPD Clinical Trials

Showing 1201-1220 of 1,604 trials

Mechanisms of Lung Defense and Their Relationship With Airway Infection in Chronic Obstructive Pulmonary Disease (COPD)

NCT01976130

Study hypothesis: Chronic Obstructive Pulmonary Disease (COPD) patients with chronic bacterial colonization have lower levels of mucins and antimicrobial peptides in their airways

Bacterial Infection in COPD

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau45 participantsStarted Jun 2012

Barcelona, Barcelona, Spain

UNKNOWNNA

E-nose Utility in the Diagnosis of Bacterial Infection in COPD

NCT01976117

Hypothesis: A commercial e-nose (Cyranose 320) is able to detect specific breathprints from patients with COPD and bacterial infection

Pulmonary Disease, Chronic Obstructive (COPD)

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauStarted Jun 2012

Barcelona, Barcelona, Spain

COMPLETEDNA

Role of Systemic Inflammation in Increase of Cardio-vascular Risk in Chronic Obstructive Pulmonary Disease

NCT02888886

The purpose is to study the correlation between systemic inflammation (serum levels of CRP, IL-1beta, IL-6 and TNF-alpha) or hyperhomocysteinemia and the increase of mortality, in a representative cohort of patients with chronic obstructive pulmonary disease (COPD). Secondary purposes are: 1. To confirm the increase of cardiovascular mortality and the importance of cardiovascular morbidity in patients with COPD, 2. To establish the role of various genetic polymorphisms in the correlation between systemic inflammation and cardiovascular disorders observed in COPD, 3. To search for acceleration of aging of cardiovascular system evaluated with carotid intima-media thickness when systemic inflammation markers are increased, 4. To study the correlation between COPD risk factors (tobacco and other food factors), change of respiratory functional data and cardiovascular morbi-mortality. In this study cardiovascular morbi-mortality is defined by following disorders: ischemic cardiopathy, left-sided heart failure, cardiac arrhythmia and cerebrovascular accident. Diagnosis is confirmed with standard techniques and independently of this study. Results of clinical examination, ECG, echocardiography and /or brain scanner will be collected.

Chronic Obstructive Pulmonary Disease

Central Hospital, Nancy, France89 participantsStarted Jul 2007

Mechanisms of Lung Defense and Their Relationship With Airway Infection in Chronic Obstructive Pulmonary Disease (COPD)

E-nose Utility in the Diagnosis of Bacterial Infection in COPD

Role of Systemic Inflammation in Increase of Cardio-vascular Risk in Chronic Obstructive Pulmonary Disease

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The Effects of Aerobic Exercise Training on Vascular, Cardiac and Cerebral Vascular Function in COPD

Regeneration of Bronchial Epithelium During Chronic Obstructive Pulmonary Disease

Validation of the AVAPS AE Algorithm in Chronic Obstructive Pulmonary Disease (COPD) Patients

Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT)

Bioequivalence Study of Synflutide HFA Inhaler and Seretide Evohaler in Healthy Volunteers Without Charcoal Block

EarlySense Monitoring Device Evaluation on COPD, CHF and Pneumonia Patients

Glycopyrrolate/Formoterol Fumarate MDI Compared With Spiriva® as An Active Control in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Comparison of Long-term Safety of the Combination Product QVA149A Against Placebo and Standard of Care Treatment in Chronic Obstructive Pulmonary Disease Patients With Moderate to Severe Airflow Limitation

Perception of Symptom Variability in COPD

Stepping up to Health - for Veterans With Chronic Obstructive Pulmonary Disease (COPD)

Exercise in Health and Chronic Obstructive Pulmonary Disease

Longitudinal Study of Cortisol and Pulmonary Function

Sources of Variability in Peak Expiratory Flow

Developing a COPD Case Finding Methodology for Primary Care

Study to Compare (COPD) Assessment Test in COPD Stage III and IV in a Prophylactic Treatment

Blood, Hair and Lung Concentrations of Metals and Metalloids in Patients With Lung Cancer or Chronic Obstructive Pulmonary Disease

Evaluation of the Lungs of Individuals With Lung Disease