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Clareo Health | COPD Clinical Trials in Philadelphia | 184 Studies

Clinical Trials COPDPhiladelphia

COPD Clinical Trials in Philadelphia

Find 184 clinical trials for copd near Philadelphia, Pennsylvania. Connect with research centers in your area.

All COPD trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 161-180 of 184 trials

CompletedLong Term Safety Study of NVA237 vs QAB149 in COPD PatientsThe purpose of the study is to provide long term safety data of NVA237. This study will assess the safety and tolerability of a single dose strength of NVA237.NCT01697696·Gulf Shores, Alabama and 60 others

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Data from ClinicalTrials.govTerms

Active not recruitingVideo Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary DiseaseThe purpose of this study is to compare the efficacy and safety of a real time video telehealth pulmonary rehabilitation intervention with standard of care in patients…NCT05119556·Birmingham, Alabama and 14 others

CompletedTrial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent® Inhalation Aerosol in COPD Patients.The objective of this study is to evaluate the efficacy and safety of 12 weeks treatment with tiotro pium HandiHaler® 18 mcg daily compared to Combivent® MDI CFC Inhalation…NCT00388882·Phoenix, Arizona and 39 others

CompletedAlvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin DeficiencyThis is a Phase 2, multicenter, double-blind, randomized (1:1), placebo-controlled, 12-week, proof-of-concept study to evaluate the safety and tolerability as well as the…NCT03679598·Birmingham, Alabama and 9 others

RecruitingmyAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the HomeParallel-group, prospective, randomized, controlled phase III trial of home High flow Nasal Therapy (HFNT) via myAirvo 3 plus usual COPD medical care vs. usual COPD medical care…NCT05204888·Birmingham, Alabama and 26 others

CompletedEffects of Roflumilast in Hospitalized Chronic Obstructive Pulmonary Disease( COPD) on Mortality and Re-hospitalizationBackground: COPD exacerbations add considerably to patients' burden because they: (1) cause frequent hospital admissions and relapses or readmissions, (2) contribute directly to…NCT01973998·Philadelphia, Pennsylvania

CompletedEffect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The HERMES Study (BY217/M2-125)The aim of the study is to compare the effect of roflumilast on exacerbation rate and pulmonary function in patients with chronic obstructive pulmonary disease (COPD).NCT00297115·Bayou La Batre, Alabama and 286 others

CompletedProof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)Primary Objective: To investigate effects of SAR440340 (anti-interleukin-33 \[IL-33\] monoclonal antibody \[mAb\]) compared with placebo, on the annualized rate of…NCT03546907·Los Angeles, California and 82 others

CompletedTiotropium +Olodaterol Fixed Dose Combination (FDC) Versus Tiotropium and Olodaterol in Chronic Obstructive Pulmonary Disease (COPD)The overall objective of this study is to assess the efficacy and safety of 52 weeks once daily treatment with orally inhaled tiotropium + olodaterol FDC (delivered by the…NCT01431287·Greer, California and 239 others

CompletedSurvival Of Subjects With Chronic Obstructive Pulmonary Disease (COPD)The purpose of this study is to see if fluticasone 500mcg/salmeterol 50mcg can improve the survival of subjects with COPD and also assess the long term safety profile of this drug.NCT00268216·Birmingham, Alabama and 458 others

CompletedEffects of Nasal High-flow Oxygen in Patients With an Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)The investigators are looking at the effect of humidified nasal high-flow with oxygen (HNHF-O2) on air exchange during exacerbations of COPD.NCT03214458·Philadelphia, Pennsylvania

Active not recruitingSafety, PK and PD Relationships of RLS-0071 in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary DiseaseAECOPD is a major cause of hospital admission and mortality. They contribute to long-term decline in lung function, physical capacity, and quality of life (QoL).NCT06175065·St. Petersburg, Florida and 3 others

CompletedStudy to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD)Primary Objective: Primary population (former smokers cohort): * Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe…NCT04751487·Phoenix, Arizona and 296 others

Enrolling by invitationGlobal Utilization And Registry Database for Improved preservAtion of doNor LUNGsThe objective of this registry is to collect and evaluate various clinical effectiveness parameters in patients with transplanted donor lung that were preserved and transported…NCT04930289·Phoenix, Arizona and 14 others

Active not recruitingA Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)The purpose of this study is to assess the long-term safety and to explore the efficacy of astegolimab in participants with chronic obstructive pulmonary disease (COPD) who have…NCT05878769·Birmingham, Alabama and 480 others

CompletedEffect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The AURA Study (BY217/M2-124)The aim of the study is to investigate the effect of roflumilast on exacerbation rate and pulmonary function in patients with chronic obstructive pulmonary disease (COPD).NCT00297102·Fullerton, California and 178 others

CompletedEfficacy, Safety and Tolerability of Two Fixed Dose Combinations of Aclidinium Bromide/Formoterol Fumarate, Aclidinium Bromide, Formoterol Fumarate and Placebo for 28-Weeks Treatment in Patients With Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD)The purpose of this Phase III study is to evaluate the long-term safety and tolerability of two fixed-dose combinations of inhaled aclidinium bromide/formoterol fumarate…NCT01572792·Anniston, Alabama and 207 others

CompletedTiotropium / Respimat One Year Study in COPD.The objective of the study is to evaluate the long-term (one year) efficacy and safety of tiotropium delivered by the Respimat inhaler in patients with COPD.NCT00387088·Birmingham, Alabama and 333 others

TerminatedBeta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary DiseaseThis is a multicenter, prospective, randomized, double-blind, placebo-controlled trial that will enroll 1028 patients with at least moderately severe COPD over a three year period…NCT02587351·Birmingham, Alabama and 26 others

CompletedEfficacy and Safety of Mepolizumab as an Add-on Treatment in Chronic Obstructive Pulmonary Disease (COPD)This is a multi-centered, randomized, placebo-controlled, double-blind, parallel group, trial evaluating 2 doses of mepolizumab against placebo given every 4 weeks through…NCT02105961·Birmingham, Alabama and 168 others

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