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Clareo Health | Colorectal Cancer Clinical Trials in Nashville | 359 Studies

Clinical Trials Colorectal CancerNashville

Colorectal Cancer Clinical Trials in Nashville

Find 359 clinical trials for colorectal cancer near Nashville, Tennessee. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Nashville

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 21-40 of 359 trials

RecruitingSafely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing ChemotherapyThis is a randomized, double-blind, placebo-controlled basket trial evaluating mifomelatide (TCMCB07) administered daily by subcutaneous (SC) injection in up to 120 patients.NCT06937177·Tucson, Arizona and 25 others

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Data from ClinicalTrials.govTerms

Active not recruitingA Study of Novel Study Interventions and Combinations in Participants With Colorectal CancerThe main purpose of this study is to evaluate the safety and efficacy of novel study interventions and combinations in participants with Colorectal Cancer (CRC).NCT06792695·Scottsdale, Arizona and 55 others

CompletedStudy of Vitamin D in Untreated Metastatic Colorectal CancerThis is a prospective, randomized, double-blind phase II trial to evaluate the efficacy and safety of two doses of vitamin D supplementation in combination with standard…NCT01516216·Boise, Idaho and 17 others

CompletedSample Collection Study to Evaluate DNA Markers in Subjects With Inflammatory Bowel Disease (IBD)The primary objective of this study is to gather stool samples from subjects with inflammatory bowel disease (IBD) to be added to a test set of stool samples that will be utilized…NCT02503696·Dothan, Alabama and 28 others

RecruitingA Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid TumorsThis is a Phase 1/2 open-label, multi-center, multi-national study with an initial dose escalation part to determine the recommended Phase II dose (RP2D) of MCLA-158 single agent…NCT03526835·La Jolla, California and 53 others

CompletedStudy of XL281 in Adults With Solid TumorsThe purpose of this study is to determine the safest dose of the multiple Raf kinase inhibitor (including c-Raf, B-Raf, and the activated mutant B-RafV600E) XL281, how often it…NCT00451880·Scottsdale, Arizona and 5 others

Active not recruitingSafety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCThis is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single…NCT04140526·Springdale, Arkansas and 36 others

Active not recruitingStudy to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid TumorsThe study will determine the recommended Phase 2 dose (RP2D) of livmoniplimab (ABBV-151) administered as monotherapy and in combination with budigalimab (ABBV-181) as well as to…NCT03821935·Springdale, Arkansas and 63 others

CompletedSotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C MutationThe aim of the study is to compare progression-free survival (PFS) in previously treated participants with Kirsten rat sarcoma (KRAS) p.G12C mutated colorectal cancer (CRC)…NCT05198934·Birmingham, Alabama and 104 others

CompletedCOM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors.This is a Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary clinical activity of COM701 as monotherapy…NCT03667716·Los Angeles, California and 10 others

CompletedA Study of Brontictuzumab With Chemotherapy for Subjects With Previously Treated Metastatic Colorectal CancerA Phase 1b Dose Escalation Study of the Safety and Pharmacodynamics of Brontictuzumab in Combination with Chemotherapy for Subjects with Previously Treated Metastatic Colorectal…NCT03031691·Denver, Colorado and 4 others

No longer availableRegorafenib in Subjects With Metastatic Colorectal Cancer (CRC) Who Have Progressed After Standard TherapyThis is a phase III B, prospective, interventional, open-label, single-arm, multicenter study to provide regorafenib to subjects diagnosed with metastatic colorectal cancer who…NCT01538680·Duarte, California and 206 others

CompletedDetection of Advanced Colorectal Neoplasia by Stool DNA in Inflammatory Bowel DiseaseThis study aims to determine the performance of the Exact IBD-ACRN surveillance test to detect colorectal cancer (CRC) and colorectal neoplasia in patients with inflammatory bowel…NCT01819766·Phoenix, Arizona and 25 others

RecruitingStudy of RMC-9805 in Participants With KRAS G12D-Mutant Solid TumorsThis study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors.NCT06040541·Sacramento, California and 16 others

CompletedA Study Combining FOLFOX or FOLFIRI With AG-013736 or Bevacizumab (Avastin) in Patients With Metastatic Colorectal Cancer After Failure Of One First Line RegimenThe study is designed to demonstrate that the combination of AG-013736 with either FOLFIRI or FOLFOX is superior to FOLFIRI or FOLFOX in combination with bevacizumab (Avastin) in…NCT00615056·Mobile, Alabama and 82 others

CompletedA Study Evaluating TAS-102 Plus Nivolumab in Patients With MSS CRCA Phase 2 Study with Safety Lead-in, Evaluating TAS-102 Plus Nivolumab in Participants with Microsatellite Stable Refractory Metastatic Colorectal CancerNCT02860546·Denver, Colorado and 2 others

CompletedA Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal CancerThis is an international multi-center, prospective, open-label, randomized, adaptive design phase 3 trial of the cancer stem cell pathway inhibitor napabucasin plus standard…NCT02753127·Birmingham, Alabama and 210 others

CompletedA Dose Finding Study of ZW49 in Patients With HER2-Positive CancersThis is a first-in-human, Phase 1, multicenter, open-label, dose-escalation study to establish the maximum-tolerated dose (MTD) or recommended dosage (RD) of ZW49, the…NCT03821233·Duarte, California and 15 others

TerminatedPhase 1 Combination Study of MM-151 With MM-121, MM-141, or TrametinibThis is a Phase 1 open-label, dose-escalation trial using "3+3" design, evaluating MM-151 co-administration with MM-121, MM-141, and trametinib at varying dose levels.NCT02538627·Aurora, Colorado and 4 others

CompletedNintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1)The objective of this Phase III study is to evaluate the efficacy of nintedanib in patients with metastatic colorectal cancer (mCRC) after failure of previous treatment with…NCT02149108·Los Angeles, California and 128 others

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