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Clareo Health | Brain Cancer Clinical Trials in Boston | 158 Studies

Clinical Trials Brain CancerBoston

Brain Cancer Clinical Trials in Boston

Find 158 clinical trials for brain cancer near Boston, Massachusetts. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Boston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 41-60 of 158 trials

TerminatedFeasibility of the LUM Imaging System for Detection of Cancer to the BrainThe overall objective of this study is to assess the safety and efficacy of the LUM Imaging System in imaging primary and metastatic cancer in the brain.NCT03717142·Boston, Massachusetts CompletedPhase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed GlioblastomaThis 2-arm, randomized, phase III study will investigate the efficacy and safety of the addition of rindopepimut (an experimental cancer vaccine that may act to promote…NCT01480479·Birmingham, Alabama and 222 others

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Data from ClinicalTrials.govTerms

CompletedGefitinib in Treating Patients With Recurrent or Progressive CNS TumorsRATIONALE: Biological therapies such as gefitinib may interfere with the growth of tumor cells and slow the growth of CNS tumors.NCT00025675·Los Angeles, California and 11 others

CompletedO6-Benzylguanine and Carmustine Implants in Treating Patients With Recurrent Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00004892·Birmingham, Alabama and 8 others

CompletedAmgen 386 for Recurrent GlioblastomaPrimary Objectives Cohort A -- monotherapy: To determine the efficacy of AMG 386 in participants with recurrent glioblastoma (GBM) as measured by 6-month progression-free…NCT01290263·Los Angeles, California and 5 others

RecruitingTargeted Pediatric High-Grade Glioma TherapyThe goal of this study is to perform genetic sequencing on brain tumors from children, adolescents, and young adult patients who have been newly diagnosed with a high-grade glioma.NCT05839379·Aurora, Colorado and 21 others

CompletedAnti-LAG-3 Alone & in Combination w/ Nivolumab Treating Patients w/ Recurrent GBM (Anti-CD137 Arm Closed 10/16/18)This phase I trial studies the safety and best dose of anti-LAG-3 (anti-LAG-3 monoclonal antibody BMS-986016) or urelumab alone and in combination with nivolumab in treating…NCT02658981·Birmingham, Alabama and 10 others

CompletedSU5416 in Treating Patients With Recurrent Astrocytoma or Mixed Glioma That Has Not Responded to Radiation TherapyRATIONALE: SU5416 may stop the growth of astrocytoma or glioma by stopping blood flow to the tumor.NCT00004868·Los Angeles, California and 11 others

RecruitingThe RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)There are no guidelines or prospective studies defining the optimal surgical treatment for gliomas of older patients (≥70 years) or those with limited functioning performance at…NCT06146725·San Francisco, California and 7 others

CompletedProcarbazine in Treating Patients With Recurrent Brain TumorRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00004004·Birmingham, Alabama and 9 others

CompletedABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma MultiformeRATIONALE: ABT-888 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high-energy x-rays to kill tumor cells.NCT00770471·Birmingham, Alabama and 10 others

TerminatedStudy Evaluating the Efficacy and Safety of Selinexor (KPT-330) in Participants With Recurrent GliomasThis is an open-label, multicenter, Phase 2 study to evaluate the efficacy and safety of oral selinexor in participants with recurrent gliomas.NCT01986348·Boston, Massachusetts and 5 others

CompletedAssessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) DisruptionThe purpose of this study is to evaluate the safety of the ExAblate Model 4000 Type 2 used as a tool to disrupt the BBB (blood brain barrier) in patients with high grade glioma…NCT03551249·Baltimore, Maryland and 3 others

CompletedSafety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma MultiformeThe purpose of this study is to determine the safety and efficacy of SL-701 as a treatment for recurrent glioblastoma multiform (GBM).NCT02078648·Birmingham, Alabama and 15 others

CompletedTemozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00047294·Boston, Massachusetts and 3 others

CompletedThalidomide, Celecoxib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Malignant GliomaRATIONALE: Thalidomide and celecoxib may stop the growth of tumor cells by stopping blood flow to the tumor.NCT00047281·Boston, Massachusetts and 2 others

CompletedBIBF 1120 for Recurrent High-Grade GliomasBIBF 1120 is a newly discovered compound that may stop cancer cells from growing abnormally.NCT01380782·Boston, Massachusetts and 3 others

CompletedComputer Planned Radiation Therapy Plus Chemotherapy in Treating Patients With Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00003417·Birmingham, Alabama and 236 others

Active not recruitingStudy of DSP-0390 in Patients With Recurrent High-Grade GliomaThis is a study of DSP-0390 in patients with recurrent high grade glioma.NCT05023551·San Francisco, California and 8 others

CompletedBoron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the BrainRATIONALE: Radiation therapy such as boron neutron capture therapy may kill tumor cells without harming normal tissue.NCT00039572·Boston, Massachusetts and 1 other

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