Once-daily Fluorometholone vs Twice-daily Cyclosporine in Dry Eye Disease

Exclusion Criteria

• •1. abnormal lid anatomy or active blepharitis
• •2. severe systemic autoimmune diseases
• •3. received permanent lacrimal plug within 3 months
• •4. DED secondary to alkali burns, cicatricial pemphigoid, or Stevens-Johnson syndrome
• •5. ocular/periocular malignancy
• •6. active ocular allergies or allergy to the study drug or its components
• •7. active infection
• •8. intraocular surgery or ocular laser surgery within 6 months
• •9. uncontrolled systemic disease or history of herpetic keratitis
• •10. contact lens user
• •11. intraocular pressure \>25mmHg
• •12. pregnancy or current breast-feeding.