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Research suggests that the type of anesthesia used for surgery may affect intraoperative stress hormone levels. There is also data to support that an increased level of stress hormones leads to increased pain after surgery. The primary aim of this study is to determine the effect of anesthesia type on long term pain after hernia surgery. In this study, patients undergoing inguinal hernia repair will be randomized to an anesthetic group, either Total Intravenous Anesthesia (TIVA) maintained with propofol or Balanced Inhaled Anesthesia (BIA) maintained with sevoflurane. This will allow us to look at any differences in short and long-term pain after hernia repair depending on type of anesthesia received.
Age
18 - No limit years
Sex
MALE
Healthy Volunteers
No
Start Date
January 1, 2015
Primary Completion Date
June 1, 2019
Completion Date
June 1, 2019
Last Updated
December 31, 2025
10
ACTUAL participants
Propofol
DRUG
Sevoflurane
DRUG
Remifentanil
DRUG
Ketamine
DRUG
Lead Sponsor
VA Pittsburgh Healthcare System
NCT07476560
NCT07461558
Data Source & Attribution
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