Finding studies
Finding studies
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Lead
AbbVie (prior sponsor, Abbott)
This is a Phase 2 study designed to evaluate the efficacy and safety of ABT-126 in approximately 260 adults with mild-to-moderate Alzheimer's disease (AD). Subjects will be randomized to one of the four treatment groups (ABT-126, donepezil, or placebo) for a 12-week Treatment Period. Acronyms are listed in the secondary outcome section, below, you will find a list of the acronyms defined: * MMSE - Mini Mental Status Exam * QoL-AD - Quality of Life - Alzheimer's Disease * CIBIC-plus - Clinician Interview-Based Impression of Change * NPI - Neuropsychiatric Inventory * CSDD - The Cornell Scale for depression in Dementia * ADCS-ADL - Alzheimer's Disease Cooperative Study - Activities of Daily Living
Age
55–90
Sex
ALL
Healthy volunteers
Not accepted