ACP-204 in Adults With Alzheimer's Disease Psychosis

Inclusion Criteria

• •Is male or female and ≥55 and ≤95 years of age living in the community or in an institutionalized setting
• •Meets clinical criteria for possible or probable AD based on the 2011 National Institute on Aging-Alzheimer Association (NIA-AA) criteria
• •Meets the revised criteria for psychosis in major or mild neurocognitive disorder established by the International Psychogeriatrics Association (IPA)
• •Has either blood-based biomarker or documented evidence (e.g. positron emission tomography, cerebrospinal fluid biomarker) indicating amyloid plaque deposition and neuropathologic change consistent with AD
• •Has a prior magnetic resonance imaging or computed tomography scan of the brain that is consistent with the diagnosis of AD
• •Meets revised criteria for psychosis in major or mild neurocognitive disorder as per International Psychogeriatrics Association
• •MMSE score ≥6 and ≤24
• •Psychotic symptoms for at least 2 months
• •Lives in a stable place of residence and there are no plans to change living arrangements
• •Has a designated study partner/caregiver
• •Able to complete all study visits with a study partner/caregiver
• •Must be on a stable dose of cholinesterase inhibitor or memantine, if applicable