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1–20 of 136
Recruiting
Biological Determinants and Neural Compensation of Dysphagia in Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder and frequently leads to oropharyngeal dysphagia, a swallowing disorder that strongly affects patient…
NCT07299448
·
Düsseldorf, North Rhine-Westphalia
Completed
Exercise Dosing Trial for Individuals With Parkinson's Disease
This is a prospective, pre-post intervention study to evaluate the effect of a high-intensity, aerobic exercise program on outcomes of cognition, mood, gait, balance…
NCT02676804
·
Charlottesville, Virginia
Terminated
Pilot Study Evaluating Safety of Unilateral Gamma Knife Subthalamotomy for Parkinson's Disease
This is a pilot study to evaluate the safety and efficacy of unilateral gamma knife subthalamotomy for Parkinson's disease in patients deemed poor candidates for deep brain…
NCT02249559
·
New York, New York
Not yet recruiting
Collection of Digital Parameters From Parts of the Neurological Examination Using an Eye Tracker
The neurological examination (NE) is a cornerstone of clinical neurology, with ocular motor assessment being a key component.
NCT07141719
·
Kiel, Schleswig-Holstein
Completed
Prospective Evaluation of Forceplate Measured Levodopa-Induced Dyskinesia
Nearly all Parkinson's disease (PD) patients eventually develop abnormal and unwanted movements (dyskinesias; LID) caused by the gold standard treatment, Levodopa.
NCT00912977
·
Portland, Oregon
Unknown
Deep Brain Stimulation (DBS) Data Base Study
The primary goal of this study is to evaluate and compare outcomes, trends, and effectiveness of both awake and asleep Deep Brain Stimulation (DBS) surgical treatments, target…
NCT01909531
·
Phoenix, Arizona
Not yet recruiting
Prescriptive Infusion Algorithm (PIA)
This study is being done to test a new way of delivering AB-1005 into the brain.
NCT07215403
·
Cleveland, Ohio and 3 others
Completed
A Multidimensional Study on Articulation Deficits in Parkinsons Disease
Articulatory deficits are present in most speakers with dysarthria, which negatively impacts their speech intelligibility, yet little is known about the relationship between…
NCT05754086
·
Tallahassee, Florida
Recruiting
GBPDC: Gut-Brain in PD Consortium Master Protocol
The purpose of this research study is to identify the role that the gut-brain axis, the group of nerves that connect the brain and gut, plays in Parkinson's disease (PD).
NCT07567794
·
Stanford, California and 6 others
Recruiting
Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)
The study is a longitudinal, multi-center study to assess progression of \[18F\] AV-133 imaging in Prodromal PD participants. Participants will be followed for up to 24 months.
NCT07265596
·
New Haven, Connecticut and 7 others
Recruiting
Directional PSA Versus STN DBS for TD-PD
The aim of this study is to compare the effectiveness of the deep brain stimulation in the posterior subthalamic area (PSA) versus the subthalamic nucleus (STN) using directional…
NCT07700862
·
Shanghai
Active not recruiting
Multimodal Tracking of Therapy Activity and Effort During Rehabilitation
This study looks at whether everyday rehabilitation therapy sessions can be recorded and measured in a more complete, objective way.
NCT07739134
·
Zurich, Canton of Zurich
Completed
Subthalamic Deep Brain Stimulation (DBS) in Parkinson's Disease
The purpose of this study is to examine the brain changes in people with Parkinson's Disease (PD) after they get deep brain stimulation (DBS) surgery, compared with people who do…
NCT02012647
·
Gainesville, Florida
Withdrawn
Attention Modulation for Treatment of Parkinson's Disease and Dementia With Lewy Bodies
The purpose of this study is to evaluate if a drug commonly used to treat excessive day-time sleepiness, called armodafinil (Nuvigil), is also effective in improving the…
NCT01256905
·
New York, New York
Completed
Study of AMDX-2011P as a Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy
The purpose of this research study is to assess safety and tolerability of a single intravenous (given through a vein) dose of the investigational retinal tracer AMDX-2011P in…
NCT05542576
·
Newport Beach, California and 1 other
Completed
Reducing Dyskinesia in Parkinson's Disease With Omega-3 Fatty Acids
The purpose of this research study is to measure the safety (side effects) of an Omega 3 Fatty acid called docosahexanoic acid (DHA) and measure the dyskinesia (involuntary…
NCT01563913
·
Portland, Oregon
Completed
A Randomized, Double-Blind, Placebo-Controlled Trial of IkT-148009 in Untreated Parkinson's Disease
This study investigates the safety and tolerability of drug IkT-148009 in untreated Parkinson's disease volunteers (30 to 80 years old).
NCT05424276
·
Scottsdale, Arizona and 27 others
Completed
Cholinergic Augmentation in Frequently Falling Subjects With Parkinson's Disease
The purpose of this study is to find out if a medication that increases levels of a brain chemical called acetylcholine will improve balance and reduce falls in patients with…
NCT00912808
Unknown
Effect of L-Dihydroxyphenylserine (L-DOPS) on Falls in Patients With Neurogenic Orthostatic Hypotension (NOH)
This will be a Phase II single center, double-blind, randomized, placebo-controlled, efficacy study. Subjects will complete six visits.
NCT03567447
·
Phoenix, Arizona
Recruiting
Neurologic Stem Cell Treatment Study
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal…
NCT02795052
·
Westport, Connecticut and 2 others
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