Transplantation of Neural Stem Cell-Derived Neurons for Parkinson's Disease

Exclusion Criteria

• •1. Patients with severe dementia and brain atrophy on MRI
• •2. Patients with severe hypertension; renal, liver, cardiac or other major organ disease; coagulopathy; cancer; other significant systemic illnesses; hepatitis, HIV
• •3. Patients older than 85 or younger than 35
• •4. Patients who withhold informed consent
• •5. Patients with a history of alcohol or drug abuse
• •6. Sexually active women of childbearing potential without adequate form of birth control
• •7. Evidence of abnormal coagulation or anticoagulant therapy
• •8. Pregnancy or lactation
• •9. History of seizure disorders or current use of antiepileptic medication
• •10. Severe cognitive impairment
• •11. Clinically significant laboratory abnormality