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1–20 of 1,293
Completed
Behavior and Activity Monitoring in MS
The investigators propose to conduct a randomized 6-month intervention study comparing cognitive functioning in individuals with relapsing-remitting multiple sclerosis assigned to…
NCT03244696
·
Columbus, Ohio
Completed
AT RISK FOR MS - Clinical Conversion of Female Monozygotic Twins Discordant for CIS/MS
The definition of the most 'at-risk' population within highly susceptible groups would provide an opportunity for preemptive therapeutics.
NCT00617383
·
Houston, Texas
Completed
Treatment Interruption of Natalizumab
This is a randomized, rater blinded trial in patients who interrupt treatment with natalizumab with or without being treated with other immunomodulatory drugs, or continue…
NCT01071083
·
Cullman, Alabama and 32 others
Unknown
Assessing Fatiguability of Tongue Muscles in MS
Multiple Sclerosis (MS) patients with subjective dysphagia will be tested for tongue strength fatigue using a strictly defined fatigue paradigm.
NCT03817073
·
Antwerp, Antwerpen
Unknown
Physical Capacity and Rehabilitation of Patients With Multiple Sclerosis
The purpose of this study is to assess the physical capacity of patients with multiple sclerosis and the effects of rehabilitation, encompassing physical therapy and physical…
NCT02352194
·
Garches
Completed
Can Vitamin D Supplementation Prevent Bone Loss in Persons With Multiple Sclerosis
Several studies have shown that bone mineral density (BMD) at the femoral neck decreases with increasing physical handicap (EDSS-score) in MS patients.
NCT00785473
·
Tromsø
Completed
A Survey to Evaluate Early Experience From Patient and Care Partner on Injection and Device for KESIMPTA® Indicated for Multiple Sclerosis
This was a US-based, observational cross-sectional study with primary data collection via questionnaires directly administered to patients with MS receiving KESIMPTA and care…
NCT05334472
·
East Hanover, New Jersey
Completed
Safety and Effectiveness of Two Doses of ABT-874 as Compared to Placebo in Subjects With Multiple Sclerosis (MS)
The objective of the trial is to study the safety and effectiveness of ABT-874 administered weekly or every other week in patients with relapsing remitting and secondary…
NCT00086671
·
Phoenix, Arizona and 43 others
Unknown
T-Cell Vaccination in Multiple Sclerosis (MS)
The purpose of this study is to evaluate the safety of T-cell vaccination in MS patients.
NCT00220428
·
Ramat Gan
Terminated
Single Center, Open Label, Study of Preparation H on Erythema in Relapsing MS Patients Treated With PLEGRIDY
The primary purpose of this single center, randomized, open label study in relapsing Multiple Sclerosis (MS) patients on PLEGRIDY (peginterferon beta-1a) is to assess the effect…
NCT02665221
·
New York, New York
Unknown
Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis
The purpose of this study is to demonstrate the superiority of MD1003 over placebo in the visual improvement of patients suffering from chronic visual loss resulting from multiple…
NCT02220244
·
Bordeaux and 19 others
Withdrawn
Rhythmic Auditory Stimulation and Walking Performance in Multiple Sclerosis (MS) Patients
The study is being conducted to determine if a home-based walking program that uses RAS (Rhythmic Auditory Stimulation)is a viable and effective treatment of gait instability for…
NCT01086371
·
Cleveland, Ohio
Unknown
Backward Masking Tasks to Decipher Impaired Input-Output Connections in MS @7T
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system.
NCT05377671
·
Marseille, Bouches Du Rhône
Completed
Mobility Enhancing Nursing Intervention
Objectives: This parallel RCT investigated the effect of a new nursing intervention (Mobility Enhancing Nursing Intervention - MFP) designed to improve the rehabilitation…
NCT02198599
·
Winterthur, Canton of Zurich
Completed
Safety and Tolerability of ISX (Isoxsuprine HCL) in MS Relapses
This is a proof of concept, randomized, double-blind, placebo-controlled, 2-arm, parallel group study of Isoxsuprine in MS subjects experiencing a typical relapse.
NCT03752307
·
Albuquerque, New Mexico
Completed
Lipoic Acid for Secondary Progressive Multiple Sclerosis (MS)
The purpose of the study is to determine if lipoic acid can protect the brain and slow disability in secondary progressive multiple sclerosis.
NCT01188811
·
Portland, Oregon
Recruiting
MB-CART2019.1 in Refractory Multiple Sclerosis
The goal of this trial is to assess the feasibility, safety and preliminary efficacy of MB-CART2019.1 in patients with active refractory primary and secondary progressive MS.
NCT07178431
·
Berlin
Not yet recruiting
Effects of Low-Load Blood Flow Restriction Exercise on Rectus Femoris Muscle Morphology in Individuals With Relapsing-Remitting Multiple Sclerosis
Multiple sclerosis (MS) is a chronic neurological disease associated with reduced muscle strength, impaired mobility, increased fatigue, and deterioration in muscle morphology.
NCT07645937
Not yet recruiting
A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy
This is an investigator-initiated, single-center, open-label study of C-CAR168, an autologous bi-specific CAR-T therapy targeting CD20 and BCMA, for the treatment of adult…
NCT07676266
·
Qingdao, Qindao, Shandong
Completed
An Intravenous Infusion Study of rHIgM22 in Patients With Multiple Sclerosis
This is a Phase I, multi-center, double-blind, randomized, placebo-controlled, dose-escalation study designed to evaluate safety, tolerability, pharmacokinetics, and…
NCT01803867
·
Long Beach, California and 16 others
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