Oral Corticotherapy in Megadoses to Treat Multiple Sclerosis During Relapse

Exclusion Criteria

• •1. First inflammatory neurological episode (relapse).
• •2. Multiple sclerosis secondary progressive or primary progressive.
• •3. The symptoms have gone on for less than 24 hours.
• •4. To be in treatment or have been treated with corticoids during the three months before.
• •5. Patients in treatment with immunosuppressors (azathioprine, mitoxantrone, ciclofosfamide...)
• •6. Pregnancy or breastfeeding or women in fertile age who don't use contraceptives measurements.
• •7. Illnesses with contraindication treatment with corticoids.
• •8. Antecedents of serious adverse effects or hypersensitive to related study medication.
• •9. Patients who wouldn´t be able to perform periodic RMN explorations, patients who are not collaborative or who need anesthesia.
• •10. Patients with intolerance to lactose.
• •11. Patients with allergy to contrast used in RMN.
• •12. Patients with chronic kidney disease.
• •13. Patients in treatment with natalizumab.