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1–20 of 6,706
Completed
Cognitive and Neurophysiological Effects of Raloxifene in Alzheimer's Disease
The aim of this study is to determine the effectiveness of treatment with raloxifene, an estrogen-like medication approved by the Food and Drug Administration for the treatment of…
NCT00065767
·
Madison, Wisconsin
Unknown
Multi-Site Evaluation of Second Step
This study is a large-scale, randomized longitudinal evaluation of Second Step: Student Success Through Prevention (Second Step - SSTP), a middle school intervention (Committee…
NCT01792167
·
Champaign, Illinois
Completed
Virtual Reality in Cognitive Stimulation Therapy for Visually Impaired Older Individuals with Dementia
Both visual impairment and dementia are prevalent in the elderly population.
NCT06793384
·
Hong Kong
Completed
Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntington´s Disease Gene Expansion Carriers
The aim of this study is to measure longitudinally the availability of the PDE10A enzyme in HDGECs using the radioligand \[18F\]MNI-659.
NCT02956148
·
Copenhagen and 6 others
Active not recruiting
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
This is a multicentre, randomized, double-blind, placebo-controlled, parallel group Phase II study to evaluate the efficacy and safety of VHB937 in participants with early AD…
NCT07094516
·
Phoenix, Arizona and 72 others
Completed
Loxapine and Weaning From Ventilator
Patients may be very agitated during the weaning period from mechanical ventilation.
NCT00122733
·
Colombes
Terminated
Safety and Tolerability of Memantine in Moderate to Severe Alzheimer's Disease
The primary objective of the study was to examine the safety and tolerability of memantine in outpatients with moderate to severe Alzheimer's Disease.
NCT00857233
·
Edmonton, Alberta and 32 others
Terminated
Investigating the Clinical Consequences of Flutemetamol-PET-scanning
The study examines subjects where there might be an indication for Amyloid-PET according to the Criteria defined by the Amyloid Imaging Task Force.
NCT02353949
·
Schlieren, Canton of Zurich
Completed
Efficacy and Safety Study for Subjects With Mild-to-Moderate Alzheimer's Disease
This is a efficacy and safety study evaluating new treatment for subjects with mild to moderate Alzheimer's Disease.
NCT00948909
·
Fresno, California and 28 others
Recruiting
Human Mesenchymal Stem Cells (hMSC) in Behavioral Problems Due to Alzheimer's Disease.
The purpose of this research study is to test if adding one infusion of mesenchymal stem cells to the current treatment with antipsychotic medication may help control behavioral…
NCT06781333
·
Miami, Florida
Withdrawn
Fortified Foods in Older Inpatients
Malnutrition in older inpatients is a significant problem espicially among those with dementia.
NCT03176030
·
Southampton
Recruiting
Brief Problem-solving Intervention in Different Formats for the Prevention of Suicide in Adults Over 50
Suicide represents a personal tragedy and an enormous global public health problem. One of the most vulnerable groups is adults 50 years and older.
NCT06338904
·
Santiago de Compostela, A Coruña
Completed
Evaluation of Efficacy and Safety of Galantamine in Patients With Dementia of Alzheimer's Type Who Failed to Benefit From Donepezil
The purpose of this study is to evaluate the efficacy and safety of galantamine in patients who failed to benefit from donepezil (patients switching from donepezil).
NCT01478633
·
Akita and 10 others
Not yet recruiting
Development and Preliminary Application Evaluation of a Clinical Decision Support Training Platform for Dementia Care
This study consists of two phases: an observational phase and a single-arm interventional phase.
NCT07823634
Terminated
The Relationship Between Neuropsychological Testing and MRI, PET and COBRE - Project 1: AIM 2 (GE-180)
The complex pathological cascades leading to both Alzheimer's disease (AD) and Parkinson's disease (PD) involve, at various points, inflammation.
NCT03702816
·
Las Vegas, Nevada
Unknown
Repetitive Transcranial Magnetic Stimulation for Apathy Treatment in Alzheimer's Disease
We aim to evaluate the safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) for apathy treatment in patients with Alzheimer's disease (AD).
NCT01885806
·
Belo Horizonte, Outside of U.S. and 1 other
Completed
Improving Quality of Life in Nursing Home Residents: A Cluster Randomized Clinical Trial of Efficacy
Improving quality of life (QoL) in residents of nursing homes: A cluster randomized clinical trial of efficacy - The KOSMOS study.
NCT02238652
·
Baerum, Akershus and 31 others
Recruiting
Study of BDNF Pathway Biomarkers in the Cerebrospinal Fluid in Patients With Huntington's Disease
Huntington disease (HD, 1.3/10 000) is an autosomal dominant disease due to an abnormal expansion of CAG triplets in HTT gene.
NCT04012411
·
Montpellier
Completed
A Family-centered Intervention for Acutely-ill Persons With Dementia
This study will address the effectiveness of Family-centered Function Focused Care (Fam-FFC).
NCT03046121
·
Lancaster, Pennsylvania and 2 others
Completed
Alzheimer's Disease Neuroimaging Initiative 3
Since its launch in 2004, the overarching aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) has been realized in informing the design of therapeutic trials in AD.
NCT02854033
·
Birmingham, Alabama and 58 others
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