Clinical Trials in San Francisco

Showing 5541-5560 of 9,883 trials

Trial of pIL-12/MK-3475 in Metastatic Melanoma

NCT02493361

This is a multicenter, Phase II, open-label, 42-patient single-arm trial of intratumoral pIL-12 electroporation (EP) in combination with pembrolizumab in patients with melanoma. Patients will be evaluated in 2 parts. Part A patients will be selected using a flow cytometric assay that quantifies intratumoral PD-1hiCD8+CTLA4+ "exhausted" lymphocytes in the tumor. Part B will enroll patients who have or are failing pembrolizumab at least 12 weeks after starting Programmed cell death protein 1 (PD-1) antibody alone or in combination, or, who have been selected using a flow cytometric assay that quantifies intratumoral PD-1hiCD8+CTLA4+ "exhausted" lymphocytes in the tumor.

Melanoma

University of California, San Francisco24 participantsStarted Aug 2015

San Francisco, California, United States • Salt Lake City, Utah, United States

COMPLETEDPhase 3< 1 mile

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

NCT01820572

The primary purpose is to assess the benefits and risks of changing from Cyclosporine or Tacrolimus to Belatacept between 6-60 months after kidney transplant.

Kidney Transplantation

Bristol-Myers Squibb446 participantsStarted Mar 2013

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Loma Linda, California, United States +114 more locations

Trial of pIL-12/MK-3475 in Metastatic Melanoma

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

Find Trials by Condition in San Francisco

Efficacy and Safety Study of CSJ148 in Stem Cell Transplant Patients

PAZIT Study for Children and Young Adults With Relapsed or Refractory Sarcoma

Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants With Severe Coronavirus Disease (COVID-19)

Gliogene: Brain Tumor Linkage Study

Study of Efficacy of PEAR-004 in Schizophrenia

Study of Safety and Efficacy of Brolucizumab 6 mg Drug Product Intended for Commercialization in Patients With nAMD

RBM-007 in Subjects witH ExudatIve Age-related Macular Degeneration

A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study)

Evaluating Anatomic Versus Targeted Lead Placement for Burst Stimulation Therapy During the Trial

Safety and Efficacy Study of Guaifenesin and Pseudoephedrine for Symptomatic Therapy to Treat Acute RTI

A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251

Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Two Orally Inhaled Indacaterol Salts in Adult Subjects With Asthma.

Safety, Tolerability, Pharmacokinetics and Efficacy of LMB763 in Patients With NASH

A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients

Topical CP-690,550 For Chronic Plaque Psoriasis

Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer

A Study of CLR325 in Chronic Stable Heart Failure Patients.

A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell Malignancies