Clinical Trials in San Francisco

Showing 2141-2160 of 12,991 trials

Safety and Usability of the Cionic Neural Sleeve for Parkinson's Disease

NCT07284823

This research will investigate the safety and usability of the Cionic Neural Sleeve Multistim System for Parkinson's Disease.

Parkinson Disease (PD)

Cionic, Inc.10 participantsStarted Dec 2025

Carlsbad, California, United States • San Francisco, California, United States

RECRUITING< 1 mile

Prospective Registry of ADC as First- and Second-line Treatment for Breast Cancer

NCT06774027

Antibody-drug conjugates (ADCs) have demonstrated substantial improvement in progression free survival (PFS) and overall survival (OS) in phase III clinical trials in patients with metastatic triple negative breast cancer (mTNBC) and hormone receptor positive/HER2 negative (HR+/HER2-) metastatic breast cancer (MBC), offering an effective new treatment strategy. Several outstanding questions drive the decision to use ADC drugs clinically. This is a prospective, multi-site observational study of patients with metastatic breast cancer (mBC) who are being treated with FDA-approved antibody drug conjugates (ADCs) as part of routine care and aims to collect real-world data to evaluate the impact of ADC treatment as part of routine care.

HER2-negative Breast CancerHER2 Negative Breast CarcinomaMetastatic Breast Cancer+3 more

University of California, San Francisco100 participantsStarted Oct 2025

San Francisco, California, United States

RECRUITINGNA< 1 mile

Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups

NCT06974773

The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis. The study also aims to assess the safety and usability of the device when used at home over several months. The main questions it aims to answer are: 1. Does at-home transcranial direct current stimulation (tDCS) reduce daily pain intensity in women with endometriosis? 2. Does the device also improve mood and sleep quality? Researchers will compare two groups-one receiving active brain stimulation and one receiving a sham (placebo) stimulation-to see if the active device provides greater improvements in symptoms. Participants will: 1. Use the NettleEndo device at home for 20 minutes per session, five times per week for 12 weeks 2. Be randomly assigned to receive either real or sham stimulation through the device 3. Complete daily and weekly symptom ratings through a mobile app 4. Be followed for 90 days after completing the intervention to monitor longer-term effects All activities are completed remotely using a smartphone app. Participants can contact the study team with questions at any time. The study is double-blind, meaning neither participants nor the researchers assessing outcomes will know who received active or sham treatment until the end of the trial.

Endometriosis

Samphire Group, Inc.120 participantsStarted Dec 2025

San Francisco, California, United States

Safety and Usability of the Cionic Neural Sleeve for Parkinson's Disease

Prospective Registry of ADC as First- and Second-line Treatment for Breast Cancer

Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups

Find Trials by Condition in San Francisco

HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP

Blue Light Cystoscopy With Cysview® Registry

A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population

A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1)

Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor

Mobile & Online-Based Interventions to Lessen Pain

Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions

Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC

Study of Aspirin in Patients With Vestibular Schwannoma

NATIENS: Optimal Management and Mechanisms of SJS/TEN

SyncAV Post-Market Trial

An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis

A Study of CNTY-101 in Participants With CD19-Positive B-Cell Malignancies

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumors