Clinical Trials in San Diego

Showing 4761-4780 of 11,146 trials

First-in-human Study of CCW702 in Patients With Metastatic Castration Resistant Prostate Cancer

NCT04077021

CCW702 is an investigational immunotherapy for prostate cancer. This is a two-part, first-in-human study to assess the safety and tolerability of CCW702 administered subcutaneously to patients with metastatic, castration resistant prostate cancer. Part I is divided in to two subparts, in both subparts patients will receive ascending dosages of CCW702 with the goal to determine the maximum tolerated dose (MTD) of CCW702 and efficacious regimen. Part Ia will explore every other other day dosing (QOD); Part Ib will explore weekly dosing (Q7D). In part II of the study, patients will be given the recommended part/phase 2 dose (RP2D) Q7D. The study will also assess the pharmacokinetics and pharmacodynamics of CCW702.

Metastatic Castration-Resistant Prostate Adenocarcinoma

Calibr, a division of Scripps Research22 participantsStarted Jul 2020

San Diego, California, United States • Baltimore, Maryland, United States • Detroit, Michigan, United States +2 more locations

COMPLETEDPhase 3< 1 mile

P3 Long Term Safety Study of Once Daily SB204 in Acne

NCT02798120

This is a multi-center, open label long-term safety (LTS) study to be conducted in approximately 600 subjects with acne vulgaris.

Acne Vulgaris

Novan, Inc.601 participantsStarted May 2016

Birmingham, Alabama, United States • Mobile, Alabama, United States • Phoenix, Arizona, United States +66 more locations

First-in-human Study of CCW702 in Patients With Metastatic Castration Resistant Prostate Cancer

P3 Long Term Safety Study of Once Daily SB204 in Acne

Find Trials by Condition in San Diego

MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)

MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)

Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients

A Study of a Potential Oral Treatment to Prevent COVID-19 in Adults Who Are Exposed to Household Member(s) With a Confirmed Symptomatic COVID-19 Infection

Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19)

rhBMP-2/CRM/CD HORIZON® Spinal System Pivotal Study

Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy

The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial

Study of ABT-199 (GDC-0199) in Combination With Azacitidine or Decitabine (Chemo Combo) in Subjects With Acute Myelogenous Leukemia (AML)

A Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Moderate to Severe Atopic Dermatitis

G1T38, a CDK 4/6 Inhibitor, in Combination With Osimertinib in EGFR-Mutant Non-Small Cell Lung Cancer

Study of TJ003234 (Anti-GM-CSF Monoclonal Antibody) in Subjects With Severe Coronavirus Disease 2019 (COVID-19)

ELUVIA™ Drug-eluting Stent Versus Zilver® PTX® Stent

A Study of Weekly Tisotumab Vedotin for Patients With Platinum-Resistant Ovarian Cancer With Safety Run-in (innovaTV 208)

Glycemic Control and the Brain in Children With Type 1 Diabetes

HBV-HIV Coinfection Research Network

A Randomized, Double Blind, Placebo Controlled Study of Etanercept in Children With Kawasaki Disease

Promoting The Self-Regulation Of Energy Intake