Clinical Trials in San Antonio

Showing 10561-10580 of 12,572 trials

Evaluating Cerebrospinal Fluid Biomarkers in Alzheimer's, Progressive Supranuclear Palsy Subjects, and Controls

NCT01348061

This is an experimental medicine study to evaluate the kinetics of cerebrospinal fluid (CSF) biomarkers in subjects with Alzheimer's disease (AD) or progressive supranuclear palsy (PSP) compared to healthy controls using a heavy water (2H2O) labeling method. This study is exploring the time profile of appearance and disappearance of pulse deuterium-labeled cargo proteins in CSF of subjects with AD and/or PSP, which is different from healthy controls, due to deficits in fast axonal transport.

Alzheimer DiseaseProgressive Supranuclear Palsy

KineMed16 participantsStarted Jul 2011

Glendale, California, United States • Eatontown, New Jersey, United States • San Antonio, Texas, United States

COMPLETEDPhase 3< 1 mile

Ranolazine Monotherapy in Subjects With Type 2 Diabetes Mellitus

NCT01472185

This is a randomized, double-blind, placebo-controlled, parallel-group, multi-center study to determine the effect of ranolazine when given as monotherapy on glycemic control in subjects with type 2 diabetes mellitus (T2DM) who were inadequately controlled with diet and exercise alone and who are treatment naive to antihyperglycemic therapy or have not received antihyperglycemic therapy in the 90 days (or thiazolidinediones \[TZDs\] for at least 24 weeks) prior to screening, and to characterize the relationship between HbA1c reduction and other glycemic parameters in subjects with T2DM.

Type 2 Diabetes Mellitus

Gilead Sciences465 participantsStarted Nov 2011

Glendale, Arizona, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +156 more locations

Evaluating Cerebrospinal Fluid Biomarkers in Alzheimer's, Progressive Supranuclear Palsy Subjects, and Controls

Ranolazine Monotherapy in Subjects With Type 2 Diabetes Mellitus

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A Dose Escalation Study of Iniparib as a Single Agent and in Combination in Solid Tumors

XL999 Administered Intravenously to a Subject With Advanced Malignancies

Efficacy & Safety of Inhaled Insulin in Type 1 Diabetes

Efficacy and Safety in Subjects With Type 2 Diabetes Receiving Subcutaneous Basal Insulin and Prandial Inhalation of Technosphere/Insulin Versus Subcutaneous Premixed Insulin Therapy Over a 52-Week Treatment Period and a 4-Week Follow-up

Food Effect of a Fixed Dose Combination of Daclatasvir, Asunaprevir and BMS-791325

To Compare Treatment With Doxorubicin or Capecitabine for Metastatic Breast Cancer in Women 60 Years and Older

VEC-162 Study in Healthy Adult Volunteers in a Model of Insomnia

VEC-162 Study in Adult Patients With Primary Insomnia

A Multicenter Study to Evaluate the Effects of a 91-day Oral Contraceptive on Bone Mineral Density in Adolescent Females

Open-Label Phase III Long-Term Safety Trial of Liprotamase

Efficacy and Safety of Tasimelteon Compared With Placebo in Totally Blind Subjects With Non-24-Hour Sleep-Wake Disorder

Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder

When to Start Anti-HIV Drugs in Patients With Opportunistic Infections

Safety and Efficacy of Technosphere® Insulin Inhalation Powder and Lantus® Compared to Humalog® and Lantus® Over 16-Weeks

Efficacy and Safety of 2 Doses of Tiotropium Respimat Compared to Placebo in Adolescents With Severe Persistent Asthma

Liprotamase Efficacy Trial in Patients With Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency

Efficacy And Safety Of Clopidogrel In Neonates /Infants With Systemic To Pulmonary Artery Shunt Palliation

Assessing the Pharmacokinetics of NKTR-118 in Subjects With Renal Impairment Compared to That in Subjects With Normal Renal Function