Clinical Trials in Pittsburgh

Showing 161-180 of 10,050 trials

A Study of Azenosertib (ZN-c3) in Participants With Solid Tumors

NCT04158336

This is a Phase 1 open-label, multicenter study of ZN-c3 (also known as Azenosertib) monotherapy which consists of Dose Escalation, a Food Effect Cohort, and Dose Expansion.

Solid Tumor

K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc274 participantsStarted Nov 2019

Tucson, Arizona, United States • Newport Beach, California, United States • Chicago, Illinois, United States +5 more locations

RECRUITINGPHASE1/PHASE2< 1 mile

Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

NCT05098132

This is a phase 1/2, multicenter, open-label study. The phase 1 portion is a dose escalation and expansion study of STK-012 as monotherapy and in combination therapy in patients with selected advanced solid tumors. The phase 2 portion is a randomized study of STK-012 in combination with standard of care (SoC) pembrolizumab, pemetrexed, and carboplatin versus SoC, in patients with first line, PD-L1 negative, non-squamous, non-small cell lung cancer.

Advanced Solid TumorNon Small Cell Lung CancerUntreated Advanced NSCLC+1 more

Synthekine364 participantsStarted Jan 2022

Tucson, Arizona, United States • Beverly Hills, California, United States • Fullerton, California, United States +24 more locations

A Study of Azenosertib (ZN-c3) in Participants With Solid Tumors

Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

Find Trials by Condition in Pittsburgh

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

The CONFORM Pivotal Trial

Study of DF1001 in Patients With Advanced Solid Tumors

A Study of DF6002 Alone and in Combination With Nivolumab

A Study of ASP1002 in Adults for Treatment of Solid Tumors

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

A Study of Ponsegromab in People With Heart Failure

A Study to Learn About the Study Medicine Called PF-07868489 in Healthy Adult People and in People With Pulmonary Arterial Hypertension

S-531011 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Advanced or Metastatic Solid Tumors

Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma

Venclose digiRF System Post Market Study

Study to Evaluate the Clinical Safety and Performance of the CorNeat KPro for Treatment of Corneal Blindness

Study of Long-Term Safety and Efficacy on Gene Therapy in Glycogen Storage Disease Type Ia