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Clareo Health | Clinical Trials in Pittsburgh | 10,741 Studies Near You

Clinical TrialsPittsburgh

Clinical Trials in Pittsburgh

Discover 10,741 clinical trials near Pittsburgh, Pennsylvania. Find research studies in your area.

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma Pancreatic Cancer

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 61-80 of 10,741 trials

CompletedA Study Evaluating Venetoclax in Combination With Low-Dose Cytarabine in Treatment-Naïve Participants With Acute Myelogenous LeukemiaThis study consists of two parts: A Phase 1 dose-escalation part that will evaluate the safety and pharmacokinetic profile of venetoclax in combination with low-dose cytarabine…NCT02287233·Kansas City, Kansas and 8 others CompletedSafety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular CoagulationThe purpose of this study is to see if ART-123 (recombinant human soluble thrombomodulin) decreases the number of people who die as a result of Disseminated Intravascular…NCT00487656·Birmingham, Alabama and 61 others

Find Trials by Condition in Pittsburgh

Breast Cancerin Pittsburgh Lung Cancerin Pittsburgh Prostate Cancerin Pittsburgh Colorectal Cancerin Pittsburgh Melanomain Pittsburgh Leukemiain Pittsburgh Lymphomain Pittsburgh Pancreatic Cancerin Pittsburgh Ovarian Cancerin Pittsburgh Brain Cancerin Pittsburgh

Data from ClinicalTrials.govTerms

Active not recruitingA Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung CancerThe purpose of this study is to assess the safety and efficacy of divarasib compared to locally approved KRAS G12C inhibitors (sotorasib or adagrasib) in participants with KRAS…NCT06497556·Gilbert, Arizona and 150 others

CompletedExpanding the Pool in Orthotopic Heart TransplantationThis is an open-label, pilot trial to test the safety and efficacy of transplantation of hearts from HCV seropositive non-viremic (HCV Ab+/NAT-) and HCV seropositive viremic (HCV…NCT03222531·Pittsburgh, Pennsylvania

CompletedStudy of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome12-week, randomized, double-blind, placebo-controlled, parallel-group study of carbetocin nasal spray for the treatment of hyperphagia in Prader-Willi syndrome (PWS)NCT06173531·Birmingham, Alabama and 29 others

Active not recruitingNeoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in MelanomaThe purpose of this study is to test the effects of anti-PI-1 inhibitor (TSR-042) or anti-PD-1/anti-TIM-3 combination (TSR-042 / TSR-022) in patients with operable melanoma.NCT04139902·Washington D.C., District of Columbia and 4 others

SuspendedTesting the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar CarcinomaThis phase I/II trial tests the safety, side effects and best dose of DT2216 in combination with irinotecan and how well it works in treating children, adolescents and young…NCT06620302·Birmingham, Alabama and 20 others

CompletedA Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)This study will evaluate the efficacy, safety and pharmacodynamics of elexacaftor (ELX, VX-445) in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects…NCT04058353·Birmingham, Alabama and 92 others

RecruitingCOMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionThis study will demonstrate the safety and effectiveness of the Edwards Lifesciences SAPIEN 3/SAPIEN 3 Ultra RESILIA Transcatheter Heart Valve (THV) Systems in subjects with a…NCT02744677·Birmingham, Alabama and 26 others

TerminatedA Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.The COMMEND Study will assess the safety and effectiveness of FLX-787 in men and women with Motor Neuron Disease \[including Amyotrophic Lateral Sclerosis (ALS), Primary Lateral…NCT03196375·Scottsdale, Arizona and 34 others

CompletedSafety and Biological Activity of Vesatolimod in HIV-1 Infected, Virologically Suppressed AdultsThe primary objectives of this study are to evaluate the safety and tolerability of escalating, multiple doses of vesatolimod (formerly GS-9620) in HIV-1 infected virologically…NCT02858401·Los Angeles, California and 7 others

TerminatedPostoperative Chemotherapy With or Without Bevacizumab for Patients With Stage II or III Rectal CancerDrugs used in chemotherapy, such as oxaliplatin, leucovorin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping…NCT00303628·Mobile, Alabama and 616 others

CompletedA Study to Assess the Efficacy and Safety of VK2809 for 52 Weeks in Subjects With Biopsy Proven NASHThe study includes 52 weeks, double-blind treatment period.NCT04173065·Madison, Alabama and 78 others

CompletedSafety and Efficacy of Etrasimod (APD334) in Patients With Ulcerative ColitisThe purpose of this study is to determine whether etrasimod is a safe and effective treatment for ulcerative colitis.NCT02447302·Birmingham, Alabama and 133 others

CompletedStudy Comparing a 13-valent Pneumococcal Conjugate Vaccine With 23-valent Pneumococcal Polysaccharide Vaccine in AdultsThis study will assess the safety, tolerability and immune response of 13-valent pneumococcal conjugate vaccine (13vPnC) compared with 23-valent Pneumococcal Polysaccharide…NCT00427895·Huntsville, Alabama and 25 others

RecruitingEvaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With AsthmaThe purpose of this study is to compare the effect of budesonide/albuterol metered-dose inhaler (BDA MDI) with albuterol sulfate metered-dose inhaler (AS MDI), both administered…NCT06307665·Anchorage, Alaska and 156 others

CompletedCombination Chemotherapy in Treating Patients With Bladder CancerRATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00014534·Scottsdale, Arizona and 284 others

CompletedA Study to Evaluate the Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Pediatric Subjects With Genotypes 1-6 Chronic Hepatitis C Virus (HCV) InfectionThe objectives of this study are to assess the pharmacokinetics, safety, and efficacy of glecaprevir/pibrentasvir adult formulation in adolescents ages 12 to 17 years and a…NCT03067129·San Francisco, California and 37 others

TerminatedSafety and Efficacy of Itacitinib in Participants With Bronchiolitis Obliterans Syndrome Following Lung TransplantationThe purpose of this study is to evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of itacitinib in participants with post-lung transplant bronchiolitis…NCT03978637·Los Angeles, California and 8 others

CompletedVascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO)This is a phase 3 study to determine the efficacy of VEGF Trap-Eye injected into the eye on vision function in subjects with macular edema as a consequence of central retinal vein…NCT00943072·Phoenix, Arizona and 60 others

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