Clinical Trials in Pittsburgh

Showing 7261-7280 of 16,007 trials

RTX-321 Monotherapy in Patients With HPV 16+ Tumors

NCT04672980

This is an open-label, multicenter, multiple-ascending dose, FIH, Phase 1 study of RTX-321 for the treatment of patients that are HLA-A\*02:01 positive with persistent, recurrent, or metastatic, unresectable, HPV 16+ cancers.

Cervical CancerHead and Neck CancerAnal Cancer

Rubius Therapeutics9 participantsStarted Apr 2021

Birmingham, Alabama, United States • Los Angeles, California, United States • Aurora, Colorado, United States +7 more locations

TERMINATEDNA< 1 mile

Heart Rate Variability and Stress Management Enhancement

NCT04381182

This study will be conducted by using two devices (Apollo and Biostrap) for monitoring of baseline physiologic variables and heart rate variability. The biostrap will be worn by residents and will monitor heart rate, heart rate variability, respiratory rate, sleep patterns, steps, etc. The Apollo is a pulse generator device aimed at modulating heart rate variability for (hopefully) reduction in stress and improving performance in and around the hospital. Resident neurosurgeons will wear the biostrap for a two week cycle and follow that with the addition of the Apollo device for heart rate variability modulation.

StressHeart Rate Variability

Joseph Maroon20 participantsStarted Sep 2021

Pittsburgh, Pennsylvania, United States

RTX-321 Monotherapy in Patients With HPV 16+ Tumors

Heart Rate Variability and Stress Management Enhancement

Find Trials by Condition in Pittsburgh

Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

Addition of ISIS 14803 to Therapy With Peginterferon and Ribavirin for Chronic Hepatitis C (HCV) Patients Not Responding Adequately to the Two Drugs

A Study to Test if TV-46000 is Safe for Maintenance Treatment of Schizophrenia

Niraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian Cancer

Open-Label, Randomised, Active Controlled, Multi-Centre Phase 3 Study Safety and Efficacy of Danaparoid vs Argatroban

Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)

The International Diabetes Closed Loop (iDCL) Trial: Protocol 1

Phase 3 Study of Hydrocodone Bitartrate Controlled-release Capsules in Subjects With Chronic Low Back Pain

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

Investigation of Sulindac (HLX-0201) and Gaboxadol (HLX-0206) in Male Fragile X Syndrome Patients Aged 13-40

Safety Study of Nivolumab to Treat Advanced or Metastatic Non-small Cell Lung Cancer

A Clinical Trial of PRAX-114 in Participants With Essential Tremor

Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia

A Study of Use of Ella®, an Emergency Contraceptive, Under Simulated OTC Conditions

S1200: Acupuncture, Sham Acupuncture, or Wait List for Joint Symptoms Related to Aromatase Inhibitors in Pts W/Early-Stage Breast Cancer

Negative Pressure Wound Therapy to Reduce Surgical Site Infection

The International Diabetes Closed Loop (iDCL) Trial: Protocol 4

DEBUT: Diverticulitis Evaluation of Patient Burden, Utilization, and Trajectory