Clinical Trials in Pittsburgh

Showing 2761-2780 of 10,050 trials

Longitudinal ctDNA Surveillance for Older Women With ER+ Breast Cancer Who Omit Surgery

NCT05914792

This prospective study recruits patients with ER+/HER2-, non-metastatic breast cancer who omit upfront surgery in favor of primary endocrine therapy for sample collection and prospective circulating tumor DNA (ctDNA) measurement to guide disease surveillance.

Breast Cancer

University of Pittsburgh49 participantsStarted Apr 2022

Pittsburgh, Pennsylvania, United States

COMPLETEDNA< 1 mile

Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis

NCT06311292

This is a small pilot study with the goal of identifying a superior sputum collection method in Cystic Fibrosis patients unable to produce a sputum. Participants will use the Volara System during clinic visit in an attempt to produce sputum.

Cystic Fibrosis

Daniel J. Weiner20 participantsStarted May 2024

Pittsburgh, Pennsylvania, United States

RECRUITINGNA< 1 mile

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

NCT03723928

This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual approach to monitoring disease.

Anatomic Stage IV Breast Cancer AJCC v8Estrogen Receptor PositiveHER2/Neu Negative+3 more

SWOG Cancer Research Network739 participantsStarted Sep 2018

Anchorage, Alaska, United States • Anchorage, Alaska, United States • Anchorage, Alaska, United States +720 more locations

Longitudinal ctDNA Surveillance for Older Women With ER+ Breast Cancer Who Omit Surgery

Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

Find Trials by Condition in Pittsburgh

Evaluation of Exotropia After Patching the Eye or After Prism Adaptation

A Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) Metastatic or Locally Advanced Breast Cancer

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

ADH1 and ADH2 Disease Monitoring Study (DMS)

Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

A Study of Long-term Effects of Vedolizumab Subcutaneous in Adults With Ulcerative Colitis and Crohn's Disease

A Study to Evaluate the Efficacy and Safety of DC-806 in Participants With Moderate to Severe Plaque Psoriasis

Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD

Safety Study of XT-150 in Participants With ALS

A Study of DS-7011a in Patients With Systemic Lupus Erythematosus

Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)

Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue

Extracellular RNA Markers of Liver Disease and Cancer

Study to Evaluate the Efficacy of a Probiotic in Infantile Colic Symptoms Relief

Study of WAL0921 in Patients With Glomerular Kidney Diseases

Effect of Tusamitamab Ravtansine on QTc Interval in Participants With Metastatic Solid Tumors